The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis

F Damas, CA Libardi, C Ugrinowitsch - European journal of applied …, 2018 - Springer
Resistance training (RT)-induced skeletal muscle hypertrophy is a highly intricate process.
Despite substantial advances, we are far from understanding exactly how muscle …

Identifying the structural adaptations that drive the mechanical load-induced growth of skeletal muscle: a scoping review

KW Jorgenson, SM Phillips, TA Hornberger - Cells, 2020 - mdpi.com
The maintenance of skeletal muscle mass plays a critical role in health and quality of life.
One of the most potent regulators of skeletal muscle mass is mechanical loading, and …

[HTML][HTML] Recent advances in understanding resistance exercise training-induced skeletal muscle hypertrophy in humans

S Joanisse, C Lim, J McKendry, JC Mcleod… - …, 2020 - ncbi.nlm.nih.gov
Skeletal muscle plays a pivotal role in the maintenance of physical and metabolic health
and, critically, mobility. Accordingly, strategies focused on increasing the quality and quantity …

Nonuniform response of skeletal muscle to heavy resistance training: Can bodybuilders induce regional muscle hypertrophy?

J ANTONIO - The Journal of Strength & Conditioning Research, 2000 - journals.lww.com
Skeletal muscle is a heterogeneous tissue that exhibits numerous inter-and intramuscular
differences (ie, architecture, fiber composition, and muscle function). An individual muscle …

[HTML][HTML] Muscle hypertrophy and muscle strength: dependent or independent variables? A provocative review

C Reggiani, S Schiaffino - European journal of translational …, 2020 - ncbi.nlm.nih.gov
The question whether the muscle hypertrophy induced by resistance training, hormone
administration or genetic manipulation is accompanied by a proportional increase in muscle …

Early skeletal muscle hypertrophy and architectural changes in response to high-intensity resistance training

OR Seynnes, M de Boer… - Journal of applied …, 2007 - journals.physiology.org
The onset of whole muscle hypertrophy in response to overloading is poorly documented.
The purpose of this study was to assess the early changes in muscle size and architecture …

Physiological differences between low versus high skeletal muscle hypertrophic responders to resistance exercise training: current perspectives and future research …

MD Roberts, CT Haun, CB Mobley… - Frontiers in …, 2018 - frontiersin.org
Numerous reports suggest there are low and high skeletal muscle hypertrophic responders
following weeks to months of structured resistance exercise training (referred to as low and …

The problem of muscle hypertrophy: revisited

SL Buckner, SJ Dankel, KT Mattocks… - Muscle & …, 2016 - Wiley Online Library
In this paper we revisit a topic originally discussed in 1955, namely the lack of direct
evidence that muscle hypertrophy from exercise plays an important role in increasing …

Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Skeletal muscle remodeling in response to eccentric vs. concentric loading: morphological, molecular, and metabolic adaptations

MV Franchi, ND Reeves, MV Narici - Frontiers in physiology, 2017 - frontiersin.org
Skeletal muscle contracts either by shortening or lengthening (concentrically or
eccentrically, respectively); however, the two contractions substantially differ from one …