[HTML][HTML] The role of exosomes in human carcinogenesis and cancer therapy—Recent findings from molecular and clinical research

K Stefańska, M Józkowiak, A Angelova Volponi… - Cells, 2023 - mdpi.com
Exosomes are biological nanoscale spherical lipid bilayer vesicles, 40–160 nm in diameter,
produced by most mammalian cells in both physiological and pathological conditions …

Exosomes in cancer theranostic: Diamonds in the rough

M Cordonnier, G Chanteloup, N Isambert… - Cell Adhesion & …, 2017 - Taylor & Francis
During the last 10 years, exosomes, which are small vesicles of 50–200 nm diameter of
endosomal origin, have aroused a great interest in the scientific and clinical community for …

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

Y Tian, S Li, J Song, T Ji, M Zhu, GJ Anderson, J Wei… - Biomaterials, 2014 - Elsevier
Targeted drug delivery vehicles with low immunogenicity and toxicity are needed for cancer
therapy. Here we show that exosomes, endogenous nano-sized membrane vesicles …

Exosomes as a drug delivery tool for cancer therapy: A new era for existing drugs and oncolytic viruses

Y Kakiuchi, S Kuroda, N Kanaya… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Exosomes are cell-derived nanovesicles involved in cell-to-cell
communications. These nanovesicles are generally considered to contain important carriers …

Emerging applications of exosomes in cancer therapeutics and diagnostics

S Inamdar, R Nitiyanandan… - … & translational medicine, 2017 - Wiley Online Library
Exosomes are nanoscale extracellular vesicles that are shed from different cells in the body.
Exosomes encapsulate several biomolecules including lipids, proteins, and nucleic acids …

Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues

SE Emam, ASA Lila, NE Elsadek, H Ando… - European Journal of …, 2019 - Elsevier
Exosomes are gaining increasing attention as drug delivery vehicles due to their low toxicity
and ability to functionally transfer biological cargos between cells. However, the therapeutic …

Phosphatidylcholine‐Engineered Exosomes for Enhanced Tumor Cell Uptake and Intracellular Antitumor Drug Delivery

Q Zhan, K Yi, X Li, X Cui, E Yang… - Macromolecular …, 2021 - Wiley Online Library
Exosomes derived from non‐tumor cells hold great potential as drug delivery vehicles
because of their good biosafety and natural transference of bioactive cargo between cells …

[HTML][HTML] From pathogenesis to clinical application: insights into exosomes as transfer vectors in cancer

W Xu, Z Yang, N Lu - Journal of Experimental & Clinical Cancer Research, 2016 - Springer
Exosomes are nanoscale extracellular membrane vesicles that are created by the fusion of
an intracellular multivesicular body with the cell membrane. They are widely distributed in …

[HTML][HTML] Forging new therapeutic targets: efforts of tumor derived exosomes to prepare the pre-metastatic niche for cancer cell dissemination and dormancy

R Bhatia, J Chang, JL Munoz, ND Walker - Biomedicines, 2023 - mdpi.com
Tumor-derived exosomes play a multifaceted role in preparing the pre-metastatic niche,
promoting cancer dissemination, and regulating cancer cell dormancy. A brief review of …

Exosomes and their role in tumorigenesis and anticancer drug resistance

N Milman, L Ginini, Z Gil - Drug Resistance Updates, 2019 - Elsevier
Exosomes are a class of extracellular vesicles ranging in size from 40 to 100 nm, which are
secreted by both cancer cells and multiple stromal cells in the tumor microenvironment …