Direct Interaction of the EpsL and EpsM Proteins of the General Secretion Apparatus in Vibrio cholerae
M Sandkvist, LP Hough, MM Bagdasarian… - Journal of …, 1999 - Am Soc Microbiol
The general secretion pathway of gram-negative bacteria is responsible for extracellular
secretion of a number of different proteins, including proteases and toxins. This pathway …
secretion of a number of different proteins, including proteases and toxins. This pathway …
Two Regions of EpsL Involved in Species-Specific Protein-Protein Interactions with EpsE and EpsM of the General Secretion Pathway inVibrio cholerae
M Sandkvist, JM Keith, M Bagdasarian… - Journal of …, 2000 - Am Soc Microbiol
Extracellular secretion of proteins via the type II or general secretion pathway in gram-
negative bacteria requires the assistance of at least 12 gene products that are thought to …
negative bacteria requires the assistance of at least 12 gene products that are thought to …
The X-ray structure of the type II secretion system complex formed by the N-terminal domain of EpsE and the cytoplasmic domain of EpsL of Vibrio cholerae
J Abendroth, P Murphy, M Sandkvist… - Journal of molecular …, 2005 - Elsevier
Gram-negative bacteria use type II secretion systems for the transport of virulence factors
and hydrolytic enzymes through the outer membrane. These sophisticated multi-protein …
and hydrolytic enzymes through the outer membrane. These sophisticated multi-protein …
Mapping Critical Interactive Sites within the Periplasmic Domain of the Vibrio cholerae Type II Secretion Protein EpsM
TL Johnson, ME Scott, M Sandkvist - Journal of bacteriology, 2007 - Am Soc Microbiol
The type II secretion (T2S) system is present in many gram-negative species, both
pathogenic and nonpathogenic, where it supports the delivery of a variety of toxins …
pathogenic and nonpathogenic, where it supports the delivery of a variety of toxins …
General secretion pathway (eps) genes required for toxin secretion and outer membrane biogenesis in Vibrio cholerae
M Sandkvist, LO Michel, LP Hough… - Journal of …, 1997 - Am Soc Microbiol
The general secretion pathway (GSP) of Vibrio cholerae is required for secretion of proteins
including chitinase, enterotoxin, and protease through the outer membrane. In this study, we …
including chitinase, enterotoxin, and protease through the outer membrane. In this study, we …
Characterization of the multimeric Eps complex required for cholera toxin secretion
M Sandkvist, M Bagdasarian, SP Howard - International journal of medical …, 2000 - Elsevier
Vibrio cholerae causes diarrheal disease through colonization of the small intestine. A
critical aspect of V. cholerae pathogenesis is its ability to actively secrete cholera toxin to the …
critical aspect of V. cholerae pathogenesis is its ability to actively secrete cholera toxin to the …
In vivo cross‐linking of EpsG to EpsL suggests a role for EpsL as an ATPase‐pseudopilin coupling protein in the Type II secretion system of Vibrio cholerae
MD Gray, M Bagdasarian, WGJ Hol… - Molecular …, 2011 - Wiley Online Library
The type II secretion system is a multi‐protein complex that spans the cell envelope of Gram‐
negative bacteria and promotes the secretion of proteins, including several virulence factors …
negative bacteria and promotes the secretion of proteins, including several virulence factors …
Molecular Analysis of the Vibrio cholerae Type II Secretion ATPase EpsE
JL Camberg, M Sandkvist - Journal of bacteriology, 2005 - Am Soc Microbiol
The type II secretion system is a macromolecular assembly that facilitates the extracellular
translocation of folded proteins in gram-negative bacteria. EpsE, a member of this secretion …
translocation of folded proteins in gram-negative bacteria. EpsE, a member of this secretion …
The dimer formed by the periplasmic domain of EpsL from the Type 2 Secretion System of Vibrio parahaemolyticus
J Abendroth, AC Kreger, WGJ Hol - Journal of structural biology, 2009 - Elsevier
The Type 2 Secretion System (T2SS), occurring in many Gram-negative bacteria, is
responsible for the transport of a diversity of proteins from the periplasm across the outer …
responsible for the transport of a diversity of proteins from the periplasm across the outer …
The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae
J Abendroth, DD Mitchell, KV Korotkov… - Journal of structural …, 2009 - Elsevier
The type 2 secretion system (T2SS), a multi-protein machinery that spans both the inner and
the outer membranes of Gram-negative bacteria, is used for the secretion of several critically …
the outer membranes of Gram-negative bacteria, is used for the secretion of several critically …
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