Emerging role of GLP-1 receptor agonists in the treatment of obesity

LM Neff, RF Kushner - … syndrome and obesity: targets and therapy, 2010 - Taylor & Francis
The prevalence of obesity has increased dramatically in recent decades, both in the US and
worldwide. Pharmacotherapy can augment the weight-reducing effects of lifestyle …

Therapies for inter-relating diabetes and obesity–GLP-1 and obesity

EW Iepsen, SS Torekov, JJ Holst - Expert opinion on …, 2014 - Taylor & Francis
Introduction: The dramatic rise in the prevalence of obesity and type 2 diabetes mellitus
(T2DM) is associated with increased mortality, morbidity as well as public health care …

Off-label antiobesity treatment in patients without diabetes with GLP-1 agonists in clinical practice

N Sauer, F Reining, CS Zur Wiesch… - Hormone and …, 2015 - thieme-connect.com
The aim of the work was to investigate whether continuation of treatment, side effects, and
effect on weight loss of GLP-1 agonists in obese patients without diabetes are equally …

Role of glucagon-like peptide 1 receptor agonists in management of obesity

D Isaacs, L Prasad-Reddy… - American journal of …, 2016 - academic.oup.com
Purpose Published data on the weight loss effects of glucagon-like peptide 1 (GLP-1)
receptor agonists are reviewed, with a focus on data from clinical trials. Summary Obesity is …

GLP-1 analogues in clinical management of obesity

R Agius, C Coelho, B McGowan - Current Opinion in Endocrine and …, 2022 - Elsevier
Obesity is a chronic disease requiring chronic management. Anti-obesity medication for the
treatment of obesity includes the glucagon-like peptide-1 (GLP-1) agonists liraglutide and …

Glucagon-like peptide-1 receptor agonists for weight loss in adult patients without diabetes

A Ottney - American journal of health-system pharmacy, 2013 - academic.oup.com
Purpose The efficacy and safety of glucagon-like peptide (GLP)-1 receptor agonists for
weight loss in adult patients without diabetes is reviewed. Summary GLP-1 receptor agonists …

Clinical efficacy of GLP-1 agonists and their place in the diabetes treatment algorithm

J Unger - Journal of Osteopathic Medicine, 2011 - degruyter.com
Incretin-based therapies (subcutaneously administered glucagon-like peptide-1 [GLP-1]
agonists and oral dipeptidyl peptidase-4 inhibitors) represent a new mechanism of action …

Glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized clinical trials

M Monami, N Marchionni… - European journal of …, 2009 - academic.oup.com
Objective The role of glucagon-like peptide-1 (GLP-1) receptor agonists in the treatment of
type 2 diabetes is debated; many recent trials, which were not included in previous meta …

Glucagon-like peptide-1 (GLP-1) receptor agonists: Differentiating the new medications

JR Unger, CG Parkin - Diabetes Therapy, 2011 - Springer
Abstract Introduction Glucagon-like peptide-1 (GLP-1) has been the focus of considerable
research activity in the treatment of type 2 diabetes mellitus (T2DM) because the incretin …

GLP-1 agonists exenatide and liraglutide: a review about their safety and efficacy

G Derosa, P Maffioli - Current Clinical Pharmacology, 2012 - ingentaconnect.com
Recently incretin-based therapies have been developed in the clinical practice, this class
includes both the dipeptidyl peptidase-4 (DPP-4) inhibitors (sitagliptin, vildagliptin …