Abstract The Developmental Origins of Health and Disease hypothesis describes how early
life environmental factors influence development in a way that impacts later health and …

For decades it has been postulated that the period in utero may be critical in modifying the
risk of adult-onset disease, although only recently has epigenetic change emerged as the …

Adverse insults during intrauterine life can result in permanent changes in the physiology
and metabolism of the offspring, which in turn leads to an increased risk of disease in …

There is ample evidence that subtle changes in the early environment, not restricted to the
fetal period but expanded to the plastic phase of early development, influence adulthood …

It is now well established that the environment to which we are exposed during fetal and
neonatal life can have a long-term impact on our health. This has been termed the …

The developmental origins of health and disease (DOHaD) hypothesis predicts that
environmental exposures experienced early in life have the potential to modify the risk …

The periconceptional period of mammalian development has been identified as an early
'developmental window'during which environmental conditions may influence the pattern of …

Prenatal origins of adult disease : Current Opinion in Obstetrics and Gynecology Prenatal
origins of adult disease : Current Opinion in Obstetrics and Gynecology Log in or Register …

Epidemiological studies have shown that the environment experienced in early life can
'programme'susceptibility to later disease. Furthermore, there is increasing evidence that …

Numerous epidemiological studies have shown that exposure to an adverse environment in
early life is associated with a substantially increased risk of later disease; a phenomenon …