Induction therapy in the modern era of combined-modality therapy for locally advanced head and neck cancer

M Posner, JB Vermorken - Seminars in oncology, 2008 - Elsevier
As therapy for locoregionally advanced head and neck cancer (HNC) has evolved, treatment
has become increasingly aggressive and cure rates have risen. However, survival still …

Induction chemotherapy in locally advanced head and neck cancers, is there a best choice?

H Mahdavi - Critical Reviews in Oncology/Hematology, 2023 - Elsevier
Locally advanced stages of squamous cancers of the head and neck (LAHNCs) acquire
high propensity for local and systemic relapse. Addition of systemic therapy as an induction …

Induction chemotherapy in locally advanced head and neck cancer: a new standard of care?

JH Lorch, MR Posner, LJ Wirth, RI Haddad - Hematology/oncology clinics of …, 2008 - Elsevier
Locally advanced squamous cell cancer of the head and neck is a major contributor to
morbidity and mortality worldwide. Despite progress through the use of multimodality …

Current status and future directions in induction chemotherapy for head and neck cancer

A Argiris - Critical Reviews in Oncology/Hematology, 2013 - Elsevier
As a component of multimodal therapy in locally advanced head and neck cancer, induction
chemotherapy represents a strategy to reduce tumor burden and target distant metastases …

The slippery role of induction chemotherapy in head and neck cancer: myth and reality

D Ferrari, MG Ghi, C Franzese, C Codecà… - Frontiers in …, 2020 - frontiersin.org
Chemoradiotherapy as an alternative to surgery can be offered to patients affected by loco-
regionally advanced head and neck cancer (HNC). Induction chemotherapy is a valid …

New options in the treatment of locally advanced head and neck cancer: role for induction chemotherapy

JJ Cruz, A Ocaña, M Navarro, E Del Barco… - Cancer treatment …, 2008 - Elsevier
Advanced locoregional disease is the most frequent clinical situation in Head and Neck
cancer. The standard of care for most clinicians is a multidisciplinary treatment with …

Induction chemotherapy meta-analysis in head and neck cancer: right answer, wrong question

AA Forastiere, DJ Adelstein, J Manola - Journal of Clinical Oncology, 2013 - ascopubs.org
Despite several decades of intensive investigation, the optimal sequencing of
chemotherapy, radiation, and surgery in the management of locoregionally advanced head …

Induction chemotherapy for head and neck cancer: recent data

EE Vokes - The oncologist, 2010 - academic.oup.com
The addition of chemotherapy to radiotherapy in the treatment of locally advanced
squamous cell carcinoma of the head and neck (SCCHN) patients improves survival. Meta …

Induction chemotherapy for locoregionally advanced head and neck cancer: past, present, future?

GJ Hanna, RI Haddad, JH Lorch - The Oncologist, 2013 - academic.oup.com
The treatment of patients with locoregionally advanced squamous cell cancer of the head
and neck is still evolving. Induction chemotherapy (IC) is widely used in this patient …

Induction chemotherapy for head and neck cancer: will history repeat itself?

A Argiris - Journal of the National Comprehensive Cancer …, 2005 - jnccn.org
Locally advanced squamous cell head and neck cancer remains a therapeutic challenge for
multidisciplinary teams. Despite high objective response rates, induction chemotherapy has …