Mechanical ventilation is an essential method of patient support, but it may induce lung
damage, leading to ventilator-induced lung injury (VILI). VILI is the result of a complex …

Mechanical ventilation applies physical stresses to the tissues of the lung and thus may give
rise to ventilator-induced lung injury (VILI), particular in patients with acute respiratory …

As currently implemented, lung protective ventilation concentrates on certain static
characteristics of the individual tidal cycle—tidal volume (TV), plateau pressure, PEEP, and …

As with most medical and pharmacologic interventions, mechanical ventilation must be
titrated within a therapeutic window, providing the required lifesustaining support while …

Pulmonary fibrosis can develop in association with genetic variants, occupational and
environmental exposures, adverse reactions to numerous medications, and many …

Ventilator-induced lung injury is a side-effect of mechanical ventilation. Its prevention or
attenuation implies knowledge of the sequence of events that lead from mechanical stress to …

The pathophysiological mechanisms by which mechanical ventilation can contribute to lung
injury, termed “ventilator-induced lung injury”(VILI), is increasingly well understood.“ …

Mechanical ventilation is a potentially life-saving therapy for patients with acute lung injury,
but the ventilator itself may cause lung injury. Ventilator-induced lung injury (VILI) is …

How ventilation strategy, specific mechanisms of mechanotransduction, and their individual
threshold values impact on VALI remains to be elucidated. In addition, clinical studies are …

Mechanical ventilation can produce lung physiological and morphological alterations
termed ventilator-induced lung injury (VILI). Early experimental studies demonstrated that …