Background Mechanical power is a summary variable including all the components which
can possibly cause VILI (pressures, volume, flow, respiratory rate). Since the complexity of …

The main supportive therapy in acute respiratory distress syndrome patients is mechanical
ventilation. As with any therapy, mechanical ventilation has side-effects, and may induce …

At the bedside, assessing the risk of ventilator-induced lung injury (VILI) requires parameters
readily measured by the clinician. For this purpose, driving pressure (DP) and end …

Objective: Mechanical ventilation (MV) has long been used as a life-sustaining approach for
several decades. However, researchers realized that MV not only brings benefits to patients …

Mechanical ventilation has been used to support acutely ill patients for several decades. But
clinicians are aware that, despite the life-saving potential of this assistance, it has several …

Ventilator-induced lung injury (VILI) is a central confounder to improving outcomes from use
of positive-pressure ventilation in critical illness. Therefore, with increasing use of positive …

For critically ill patients, mechanical ventilation is a commonly used life-supporting modality,
but ventilation per se could also induce lung injury. Mechanical forces–induced cell damage …

The last two decades have brought new insights into mechanisms of lung injury. These
insights have profoundly altered the ventilator management of patients with adult respiratory …

Despite advances in critical care, the mortality rate in patients with acute lung injury remains
high. Furthermore, most patients who die do so from multisystem organ failure. It has been …

It is well established that mechanical ventilation can injure the lung, producing an entity
known as ventilator-induced lung injury (VILI). There are various forms of VILI, including …