Low-abundance drug-resistant HIV-1 variants: finding significance in an era of abundant diagnostic and therapeutic options
RW Shafer - The Journal of infectious diseases, 2009 - academic.oup.com
Several prospective and retrospective studies have shown that genotypic testing for drug-
resistant HIV-1 variants has helped health-care providers better understand patient …
resistant HIV-1 variants has helped health-care providers better understand patient …
New technology to detect low-level drug-resistant HIV variants
A Gega, MJ Kozal - Future virology, 2011 - Taylor & Francis
Genotypic assays to detect HIV drug resistance are recommended for use in the routine
clinical care of HIV-infected persons. Genotypic resistance assays have demonstrated good …
clinical care of HIV-infected persons. Genotypic resistance assays have demonstrated good …
Minority variants of drug-resistant HIV
S Gianella, DD Richman - The Journal of infectious diseases, 2010 - academic.oup.com
Minor drug-resistant variants exist in every patient infected with human immunodeficiency
virus (HIV). Because these minority variants are usually present at very low levels, they …
virus (HIV). Because these minority variants are usually present at very low levels, they …
[PDF][PDF] Update of the drug resistance mutations in HIV-1: Fall 2006
VA Johnson, F Brun-Vézinet, B Clotet, DR Kuritzkes… - Top HIV Med, 2006 - iasusa.org
The International AIDS Society–USA (IAS–USA) Drug Resistance Mutations Group is
marking 6 years as an independent volunteer panel of experts focused on identifying key …
marking 6 years as an independent volunteer panel of experts focused on identifying key …
The role of HIV-1 drug-resistant minority variants in treatment failure
N Stella-Ascariz, JR Arribas… - The Journal of …, 2017 - academic.oup.com
Human immunodeficiency virus type 1 (HIV-1) drug resistance genotyping is recommended
to help in the selection of antiretroviral therapy and to prevent virologic failure. There are …
to help in the selection of antiretroviral therapy and to prevent virologic failure. There are …
When do minority drug-resistant HIV-1 variants have a major clinical impact?
W Heneine - The Journal of infectious diseases, 2010 - academic.oup.com
accepted 1 December 2009; electronically published 26 January 2010. Potential conflicts of
interest: WH is named on a patent application on the use of the real-time polymerase chain …
interest: WH is named on a patent application on the use of the real-time polymerase chain …
Low-frequency HIV-1 drug resistance mutations can be clinically significant but must be interpreted with caution
JA Johnson, AM Geretti - Journal of antimicrobial chemotherapy, 2010 - academic.oup.com
With drug-resistant HIV-1 present in at least 10%–20% of new infections in Western
countries and in> 60% of patients failing antiretroviral therapy (ART), monitoring HIV-1 drug …
countries and in> 60% of patients failing antiretroviral therapy (ART), monitoring HIV-1 drug …
Understanding HIV-1 drug resistance
LM Frenkel, NH Tobin - Therapeutic drug monitoring, 2004 - journals.lww.com
Infection with drug-resistant HIV-1 may result from the acquisition of mutant strains or from
their selection within the individual; either can compromise the efficacy of antiretroviral …
their selection within the individual; either can compromise the efficacy of antiretroviral …
Clinical implications of HIV-1 minority variants
JZ Li, DR Kuritzkes - Clinical infectious diseases, 2013 - academic.oup.com
Technologic advances in human immunodeficiency virus type 1 (HIV-1) sequencing have
revolutionized the study of antiretroviral drug resistance and are increasingly moving from …
revolutionized the study of antiretroviral drug resistance and are increasingly moving from …
[PDF][PDF] Update of the drug resistance mutations in HIV-1: 2007
VA Johnson, F Brun-Vézinet, B Clotet, HF Gunthard… - Top HIV Med, 2007 - iasusa.org
This version of the International AIDS Society–USA (IAS-USA) Drug Resistance Mutations
Figures updates the figures published in this journal in August/September 2006. 1 The IAS …
Figures updates the figures published in this journal in August/September 2006. 1 The IAS …