Nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated cation channels
well characterized in neuronal signal transmission. Moreover, recent studies have revealed …

Objective: Type 2 diabetes (T2D) occurs by deterioration in pancreatic β-cell function and/or
progressive loss of pancreatic β-cell mass under the context of insulin resistance. α7 …

Nicotinic acetylcholine receptors (nAChRs) are pentameric, neurotransmitter-gated ion
channels responsible for rapid excitatory neurotransmission in the central and peripheral …

Progress in the fields of neuroscience and molecular biology has identified the forebrain
cholinergic system as being important in many higher order brain functions. Further analysis …

Nicotine alters appetite and energy expenditure, leading to changes in body weight. While
the exact mechanisms underlying these effects are not fully established, both central and …

The α6 subunit of the nicotinic acetylcholine receptor (nAChR) is expressed at very high
levels in dopaminergic (DA) neurons. However, because of the lack of pharmacological …

Neuronal nicotinic acetylcholine receptors (nAChR) are composed of 12 subunits (α2–α10
and β2–β4), which play the central role in autonomic transmission. β4 subunits are …

The α7nicotinic receptor (nAChR) is a major subtype of the nAChRs in the central nervous
system, and the receptor plays an important role in brain function. In the dbSNP database …

Transcripts for the β2 and the β4 nicotinic acetylcholine receptor (nAChR) subunits are
found throughout the CNS and the peripheral nervous system. These two β subunits can …

Cigarette smoking causes insulin resistance. However, nicotine induces anti-inflammation
and improves glucose tolerance in insulin-resistant animal models. Here, we determined the …