Adenosine A 2A receptors, which have been cloned from several mammalian species, are
activated by physiological concentrations of adenosine to stimulate the formation of cAMP …

Recent advances in molecular biology, biochemistry, cell biology and behavioral
pharmacology together with the development of more selective ligands to the various …

Adenosine A2A receptors were cloned about ten years ago and are known to be well
conserved among mammals. Rather selective agonists and antagonists are available. In …

1. Adenosine is an endogenous neuromodulator that exerts its depressant effect on neurons
by acting on the A 1 adenosine receptor subtype. Excitatory actions of adenosine, mediated …

It is well known that the nucleoside adenosine exerts a modulatory influence in the central
nervous system by activating G protein coupled receptors. Adenosine A2A receptors, the …

The distribution, molecular structure and role of adenosine A2 receptors in the nervous
system, is reviewed. The adenosine A2a receptor subtype, identified in the nervous system …

Adenosine's diverse physiological functions are mediated by four subtypes of receptors (A1,
A2A, A2B and A3). The A1 adenosine receptor pharmacology and therapeutic application of …

Adenosine regulates many physiological functions through specific cell membrane
receptors. On the basis of pharmacological studies and molecular cloning, four different …

The adenosine A2A receptor subtype is one of the four adenosine receptors that have been
identified in the mammalian organism. In addition to being found in blood vessels, platelets …

Adenosine is an endogenous nucleoside that modulates many physiological processes. Its
actions are mediated by interaction with specific cell membrane receptors. Four subtypes of …