Chondroitinase-mediated degradation of rare 3-O-sulfated glucuronic acid in functional oversulfated chondroitin sulfate K and E

D Fongmoon, AK Shetty, S Yamada, M Sugiura… - Journal of Biological …, 2007 - ASBMB
Chondroitin sulfate K (CS-K) from king crab cartilage rich in rare 3-O-sulfated glucuronic
acid (GlcUA (3S)) displayed neuritogenic activity and affinity toward various growth factors …

Novel sulfated oligosaccharides containing 3-O-sulfated glucuronic acid from king crab cartilage chondroitin sulfate K: unexpected degradation by chondroitinase …

K Sugahara, Y Tanaka, S Yamada, N Seno… - Journal of Biological …, 1996 - ASBMB
We prepared a series of oligosaccharides from king crab cartilage chondroitin sulfate K after
exhaustive digestion with testicular hyaluronidase, and determined the structures of four …

Functional chondroitin sulfate from Enteroctopus dofleini containing a 3-O-sulfo glucuronic acid residue

K Higashi, Y Okamoto, A Mukuno, J Wakai… - Carbohydrate …, 2015 - Elsevier
There are several reports that chondroitin sulfate containing K-type units [GlcA (3S)-GalNAc
(4S)] exhibiting similar levels of neurite outgrowth promoting activities as CS having high …

Structural studies on the chondroitinase ABC-resistant sulfated tetrasaccharides isolated from various chondroitin sulfate isomers

K Sugahara, K Shigeno, M Masuda, N Fujii… - Carbohydrate …, 1994 - Elsevier
Various commercially available chondroitin sulfates, including an A isomer from whale
cartilage, C and D isomers from shark cartilage, and an E isomer from squid cartilage, were …

Sulphation heterogeneity in the trisaccharide (GalNAcSβ1,4GlcAβ1,3GalNAcS) isolated from the non-reducing terminal of human aggrecan chondroitin sulphate

LA WEST, P ROUGHLEY, FRT NELSON… - Biochemical …, 1999 - portlandpress.com
We report here the isolation and sulphation isomer analyses of trisaccharides GalNAcS (β1,
4) GlcA (β1, 3) GalNAcS (in which S indicates sulphate) derived from the non-reducing …

[HTML][HTML] A chondroitin sulfate and hyaluronic acid lyase with poor activity to glucuronyl 4, 6-O-disulfated N-acetylgalactosamine (E-type)–containing structures

C Peng, Q Wang, S Wang, W Wang, R Jiao… - Journal of Biological …, 2018 - ASBMB
GlcUAβ1–3GalNAc (4S, 6S)(E unit)–rich domains have been shown to play key roles in
various biological functions of chondroitin sulfate (CS). However, an enzyme that can …

A unique nonreducing terminal modification of chondroitin sulfate by N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase

S Ohtake, K Kimata, O Habuchi - Journal of biological chemistry, 2003 - ASBMB
N-Acetylgalactosamine 4-sulfate 6-O-sulfotransferase (GalNAc4S-6ST) transfers sulfate from
3′-phosphoadenosine 5′-phosphosulfate (PAPS) to position 6 of N-acetylgalactosamine …

Highly sulfated hexasaccharide sequences isolated from chondroitin sulfate of shark fin cartilage: insights into the sugar sequences with bioactivities

S Mizumoto, S Murakoshi, K Kalayanamitra… - …, 2013 - academic.oup.com
Chondroitin sulfate (CS) chains regulate the development of the central nervous system in
vertebrates and are linear polysaccharides consisting of variously sulfated repeating …

Regulation of chondroitin sulfate biosynthesis by specific sulfation: acceptor specificity of serum β-GalNAc transferase revealed by structurally defined …

H Kitagawa, K Tsutsumi, M Ujikawa, F Goto… - …, 1997 - academic.oup.com
The relationship between sulfation and polymerization in chondroitin sulfate (CS)
biosynthesis has been poorly understood. In this study, we investigated the specificity of …

Chondroitinase ABC-resistant sulfated trisaccharides isolated from digests of chondroitin/dermatan sulfate chains

K Sugahara, Y Takemura, M Sugiura, Y Kohno… - Carbohydrate …, 1994 - Elsevier
Four kinds of sulfated trisaccharides resistant to chondroitinase ABC were isolated after
chondroitinase B or ABC treatment of dermatan sulfate or various chondroitin sulfate …