[HTML][HTML] Great ape genetic diversity and population history
Most great ape genetic variation remains uncharacterized,; however, its study is critical for
understanding population history,,,, recombination, selection and susceptibility to disease …
understanding population history,,,, recombination, selection and susceptibility to disease …
Great ape DNA sequences reveal a reduced diversity and an expansion in humans
H Kaessmann, V Wiebe, G Weiss, S Pääbo - Nature genetics, 2001 - nature.com
The extent of DNA sequence variation of chimpanzees is several-fold greater than that of
humans 1. It is unclear, however, if humans or chimpanzees are exceptional among …
humans 1. It is unclear, however, if humans or chimpanzees are exceptional among …
Admixture mapping for hypertension loci with genome-scan markers
Identification of genetic variants that contribute to risk of hypertension is challenging. As a
complement to linkage and candidate gene association studies, we carried out admixture …
complement to linkage and candidate gene association studies, we carried out admixture …
Returning incidental findings in African genomics research
A Wonkam, J de Vries - Nature Genetics, 2020 - nature.com
Returning incidental findings in African genomics research | Nature Genetics Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …
content Thank you for visiting nature.com. You are using a browser version with limited support …
[HTML][HTML] Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits
Next-generation association studies can be empowered by sequence-based imputation and
by studying founder populations. Here we report∼ 9.5 million variants from whole-genome …
by studying founder populations. Here we report∼ 9.5 million variants from whole-genome …
A reference panel of 64,976 haplotypes for genotype imputation
Nature genetics, 2016 - nature.com
We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs
constructed using whole-genome sequence data from 20 studies of predominantly …
constructed using whole-genome sequence data from 20 studies of predominantly …
Signatures of natural selection in the human genome
M Bamshad, SP Wooding - Nature Reviews Genetics, 2003 - nature.com
During their dispersal from Africa, our ancestors were exposed to new environments and
diseases. Those who were better adapted to local conditions passed on their genes …
diseases. Those who were better adapted to local conditions passed on their genes …
Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa
Characterizing genetic diversity in Africa is a crucial step for most analyses reconstructing
the evolutionary history of anatomically modern humans. However, historic migrations from …
the evolutionary history of anatomically modern humans. However, historic migrations from …
The beauty of admixture
A Darvasi, S Shifman - Nature genetics, 2005 - nature.com
The beauty of admixture | Nature Genetics Skip to main content Thank you for visiting nature.com.
You are using a browser version with limited support for CSS. To obtain the best experience …
You are using a browser version with limited support for CSS. To obtain the best experience …
Human origins in a southern African palaeo-wetland and first migrations
Anatomically modern humans originated in Africa around 200 thousand years ago (ka) 1, 2,
3, 4. Although some of the oldest skeletal remains suggest an eastern African origin 2 …
3, 4. Although some of the oldest skeletal remains suggest an eastern African origin 2 …