Building and characterizing antibody-targeted lipidic nanotherapeutics

DB Kirpotin, CO Noble, ME Hayes, Z Huang… - Methods in …, 2012 - Elsevier
Immunoliposomes provide a complementary, and in many instances advantageous, drug
delivery strategy to antibody-drug conjugates. Their high carrying capacity of 20,000 …

[HTML][HTML] Biomimetic liposomes hybrid with erythrocyte membrane modulate dendritic cells to ameliorate systemic lupus erythematosus

X Hao, J Gan, J Cao, D Zhang, J Liang, L Sun - Materials Today Bio, 2023 - Elsevier
Dendritic cells (DCs)-based immunotherapy has shown immense promise in systemic lupus
erythematosus (SLE) treatment. However, existing carrier strategies such as polymers …

Biologia Futura: Emerging antigen-specific therapies for autoimmune diseases

G Sármay - Biologia futura, 2021 - Springer
Autoimmune diseases are caused by breaking the central and/or peripheral tolerance
against self, leading to uncontrolled immune response to autoantigens. The incidences of …

Therapeutic applications of nanomedicine in autoimmune diseases: from immunosuppression to tolerance induction

M Gharagozloo, S Majewski, M Foldvari - … : Nanotechnology, Biology and …, 2015 - Elsevier
Autoimmune diseases are chronic, destructive diseases that can cause functional disability
and multiple organ failure. Despite significant advances in the range of therapeutic agents …

Immunoliposomes: A review on functionalization strategies and targets for drug delivery

JO Eloy, R Petrilli, LNF Trevizan, M Chorilli - Colloids and Surfaces B …, 2017 - Elsevier
Nanoparticles, especially liposomes, have gained prominence in the field of drug delivery
for the treatment of human diseases, particularly cancer; they provide several advantages …

Delivery Route Considerations for Designing Antigen‐Specific Biomaterial Strategies to Combat Autoimmunity

MA Ackun-Farmmer, CM Jewell - Advanced nanobiomed …, 2023 - Wiley Online Library
Disease‐modifying drugs and biologics used to treat autoimmune diseases, although
promising, are non‐curative. As the field moves toward development of new approaches to …

Engineering antigen-presenting cells for immunotherapy of autoimmunity

CT Smith, Z Wang, JS Lewis - Advanced Drug Delivery Reviews, 2024 - Elsevier
Autoimmune diseases are burdensome conditions that affect a significant fraction of the
global population. The hallmark of autoimmune disease is a host's immune system being …

Therapeutic liposomal vaccines for dendritic cell activation or tolerance

NA Nagy, AM De Haas, TBH Geijtenbeek… - Frontiers in …, 2021 - frontiersin.org
Dendritic cells (DCs) are paramount in initiating and guiding immunity towards a state of
activation or tolerance. This bidirectional capacity of DCs sets them at the center stage for …

Autoantigen‐Dexamethasone Conjugate‐Loaded Liposomes Halt Arthritis Development in Mice

N Benne, D Ter Braake, D Porenta… - Advanced …, 2024 - Wiley Online Library
There is no curative treatment for chronic auto‐inflammatory diseases including rheumatoid
arthritis, and current treatments can induce off‐target side effects due to systemic immune …

Tolerogenic lipid nanoparticles for delivering self-antigen mRNA for the treatment of experimental autoimmune encephalomyelitis

M Gomi, Y Nakayama, Y Sakurai, R Oyama, K Iwasaki… - Pharmaceuticals, 2023 - mdpi.com
Multiple sclerosis is a disease caused by autoantigen-responsive immune cells that disrupt
the myelin in the central nervous system (CNS). Although immunosuppressive drugs are …