[引用][C] Adverse immune effects of liposomes: complement activation, immunogenicity and immune suppression

J Szebeni, Y Barenholz - Harnessing …, 2009 - Pan Stanford Publishing Singapore

Overcoming challenges in treating autoimmuntity: development of tolerogenic immune-modifying nanoparticles

RM Pearson, JR Podojil, LD Shea, NJC King… - … , Biology and Medicine, 2019 - Elsevier
Autoimmune diseases, such as celiac disease, multiple sclerosis, and type 1 diabetes, are
leading causes of morbidity and mortality in the United States. In these disease states …

Encapsulating an immunosuppressant enhances tolerance induction by Siglec‐engaging tolerogenic liposomes

L Pang, MS Macauley, BM Arlian, CM Nycholat… - …, 2017 - Wiley Online Library
Unwanted antibody responses significantly impact human health, and current options for
treating deleterious antibody responses largely rely on broad immunosuppressants that can …

Nanoengineering Apolipoprotein A1‐Based Immunotherapeutics

DP Schrijver, A de Dreu, SRJ Hofstraat… - Advanced …, 2021 - Wiley Online Library
In the slipstream of targeting the adaptive immune system, innate immunotherapy strategies
are being developed. In this context, technologies based on natural carrier vehicles that …

A step-by-step approach to improve clinical translation of liposome-based nanomaterials, a focus on innate immune and inflammatory responses

G Della Camera, D Lipsa, D Mehn, P Italiani… - International Journal of …, 2021 - mdpi.com
This study aims to provide guidelines to design and perform a robust and reliable physical-
chemical characterization of liposome-based nanomaterials, and to support method …

Nanomaterials for antigen-specific immune tolerance therapy

J Park, Y Wu, Q Li, J Choi, H Ju, Y Cai, J Lee… - Drug Delivery and …, 2023 - Springer
Impairment of immune tolerance might cause autologous tissue damage or overactive
immune response against non-pathogenic molecules. Although autoimmune disease and …

mRNA Lipid Nanoparticles for Ex Vivo Engineering of Immunosuppressive T Cells for Autoimmunity Therapies

AS Thatte, AG Hamilton, BE Nachod, AJ Mukalel… - Nano Letters, 2023 - ACS Publications
Cell-based therapies for autoimmune diseases have gained significant traction, with several
approaches centered around the regulatory T (Treg) cell─ a well-known …

[PDF][PDF] Engineering tolerance using biomaterials to target and control antigen presenting cells

LH Tostanoski, EA Gosselin, CM Jewell - Discov. Med, 2016 - jewell.umd.edu
Autoimmune diseases occur when cells of the adaptive immune system incorrectly
recognize and attack “self” tissues. Importantly, the proliferation and differentiation of these …

Effective transcutaneous immunization by antigen-loaded flexible liposome in vivo

N Li, L Peng, X Chen, S Nakagawa… - International journal of …, 2011 - Taylor & Francis
Background Transcutaneous vaccines have received wide attention due to their easy-to-
use, needle-free, noninvasive delivery. However, the novel barrier function of stratum …

Nano and microparticle emerging strategies for treatment of autoimmune diseases: multiple sclerosis and type 1 diabetes

AJ Kwiatkowski, JM Stewart, JJ Cho… - Advanced …, 2020 - Wiley Online Library
Autoimmune diseases affect 10% of the world's population, and 1 in 200 people worldwide
suffer from either multiple sclerosis (MS) or type 1 diabetes (T1D). While the targeted organ …