For as many as 30% of epilepsy patients, seizures are poorly controlled with medication
alone. For some of these patients surgery may be an option: the brain region responsible for …

Background The surgical treatment of patients with intractable epilepsy is preceded by a pre-
surgical evaluation period during which intracranial EEG recordings are performed to …

OBJECTIVE: To discriminate seizures from interictal dynamics based on multivariate
synchrony measures, and to identify dynamics of a pre-seizure state. METHODS: A linear …

This research study is part of a therapy development effort in which a novel approach was
taken to develop an implantable electroencephalographic (EEG) based brain monitoring …

Stereoelectroencephalography (depth-EEG signals) is a presurgical investigation technique
of drug-resistant partial epilepsy, in which multiple sensor intracerebral electrodes are used …

Beginning in the 1970s engineers designed systems to predict epileptic seizures based
upon quantitative changes in the electroencephalogram, which they hypothesized began …

Research in seizure prediction has come a long way since its debut almost 4 decades ago.
Early studies suffered methodological caveats leading to overoptimistic results and lack of …

Object: Subdural or deep intracerebral electrodes are essential in order to precisely localize
epileptic zone in patients with medically intractable epilepsy. Precise localization of the …

Localizing hyperexcitable brain tissue to treat focal seizures remains challenging. We want
to identify the seizure onset zone from interictal EEG biomarkers. We hypothesize that a …