Local delivery of doxorubicin prodrug via lipid nanocapsule–based hydrogel for the treatment of glioblastoma
M Wang, R Bergès, A Malfanti, V Préat… - Drug delivery and …, 2023 - Springer
Glioblastoma (GBM) recurrences appear in most cases around the resection cavity borders
and arise from residual GBM cells that cannot be removed by surgery. Here, we propose a …
and arise from residual GBM cells that cannot be removed by surgery. Here, we propose a …
Injectable nanomedicine hydrogel for local chemotherapy of glioblastoma after surgical resection
C Bastiancich, J Bianco, K Vanvarenberg… - Journal of controlled …, 2017 - Elsevier
Glioblastoma (GBM) treatment includes, when possible, surgical resection of the tumor
followed by radiotherapy and oral chemotherapy with temozolomide, however recurrences …
followed by radiotherapy and oral chemotherapy with temozolomide, however recurrences …
Glioblastoma-targeted, local and sustained drug delivery system based on an unconventional lipid nanocapsule hydrogel
C Gazaille, E Bozzato, N Madadian-Bozorg… - Biomaterials …, 2023 - Elsevier
The objective of this work was to develop an implantable therapeutic hydrogel that will
ensure continuity in treatment between surgery and radiochemotherapy for patients with …
ensure continuity in treatment between surgery and radiochemotherapy for patients with …
Evaluation of lauroyl-gemcitabine-loaded hydrogel efficacy in glioblastoma rat models
C Bastiancich, L Lemaire, J Bianco, F Franconi… - …, 2018 - Taylor & Francis
Aim: Anticancer drug-loaded hydrogels are a promising strategy for the local treatment of
incurable brain tumors such as glioblastoma (GBM). Recently, we demonstrated the efficacy …
incurable brain tumors such as glioblastoma (GBM). Recently, we demonstrated the efficacy …
Drug combination using an injectable nanomedicine hydrogel for glioblastoma treatment
Lauroyl-gemcitabine lipid nanocapsules (GemC 12-LNC) hydrogel, administered
intratumorally or perisurgically in the tumor resection cavity, increases animal survival in …
intratumorally or perisurgically in the tumor resection cavity, increases animal survival in …
Dual-drug loaded nanomedicine hydrogel as a therapeutic platform to target both residual glioblastoma and glioma stem cells
Glioblastoma (GBM) recurrences are inevitable, and mainly originate from residual tumor
cells and the presence of glioma stem cells (GSC) around the resection cavity borders. We …
cells and the presence of glioma stem cells (GSC) around the resection cavity borders. We …
Lauroyl-gemcitabine-loaded lipid nanocapsule hydrogel for the treatment of glioblastoma
C Bastiancich, K Vanvarenberg, B Ucakar… - Journal of Controlled …, 2016 - Elsevier
The local delivery of chemotherapeutic agents is a very promising strategy for the treatment
of glioblastoma (GBM). Gemcitabine is a chemotherapeutic agent that has a different …
of glioblastoma (GBM). Gemcitabine is a chemotherapeutic agent that has a different …
Doxorubicin-loaded liposome-like particles embedded in chitosan/hyaluronic acid-based hydrogels as a controlled drug release model for local treatment of …
Glioblastoma (GBM) resection and medication treatment are limited, and local drug
therapies are required. This study aims to create a hybrid system comprising liposome-like …
therapies are required. This study aims to create a hybrid system comprising liposome-like …
Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma
Among central nervous system tumors, Glioblastoma (GBM) is the most common, aggressive
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …
Liposome-based glioma targeted drug delivery enabled by stable peptide ligands
The treatment of glioma is one of the most challenging tasks in clinic. As an intracranial
tumor, glioma exhibits many distinctive characteristics from other tumors. In particular …
tumor, glioma exhibits many distinctive characteristics from other tumors. In particular …
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