[HTML][HTML] Multi-parameter flow cytometry immunophenotyping distinguishes different stages of tuberculosis infection
O Estévez, L Anibarro, E Garet, A Martínez, A Pena… - Journal of Infection, 2020 - Elsevier
Objectives To identify new potential host biomarkers in blood to discriminate between active
TB patients, uninfected (NoTBI) and latently infected contacts (LTBI). Methods A blood cell …
TB patients, uninfected (NoTBI) and latently infected contacts (LTBI). Methods A blood cell …
CD38+CD27–TNF-α + on Mtb-specific CD4+ T Cells Is a Robust Biomarker for Tuberculosis Diagnosis
MP Acharya, SP Pradeep, VS Murthy… - Clinical Infectious …, 2021 - academic.oup.com
Background Early and accurate diagnosis followed by timely treatment are the key
prerequisites to fight tuberculosis (TB) and reduce its global burden. Despite scientific …
prerequisites to fight tuberculosis (TB) and reduce its global burden. Despite scientific …
Differential Expression of Activation Markers by Mycobacterium tuberculosis-specific CD4+ T Cell Distinguishes Extrapulmonary From Pulmonary Tuberculosis and …
PS Silveira-Mattos, B Barreto-Duarte… - Clinical Infectious …, 2020 - academic.oup.com
Background Diagnosis of active tuberculosis (ATB) currently relies on detection of
Mycobacterium tuberculosis (Mtb). Identifying patients with extrapulmonary TB (EPTB) …
Mycobacterium tuberculosis (Mtb). Identifying patients with extrapulmonary TB (EPTB) …
[HTML][HTML] Phenotypic changes on Mycobacterium tuberculosis-specific CD4 T cells as surrogate markers for tuberculosis treatment efficacy
MIM Ahmed, NE Ntinginya, G Kibiki, BA Mtafya… - Frontiers in …, 2018 - frontiersin.org
Background: The analysis of phenotypic characteristics on Mycobacterium tuberculosis
(MTB)-specific T cells is a promising approach for the diagnosis of active tuberculosis (aTB) …
(MTB)-specific T cells is a promising approach for the diagnosis of active tuberculosis (aTB) …
[HTML][HTML] Activation Phenotype of Mycobacterium tuberculosis-Specific CD4+ T Cells Promoting the Discrimination Between Active Tuberculosis and Latent …
Y Luo, Y Xue, L Mao, Q Lin, G Tang, H Song… - Frontiers in …, 2021 - frontiersin.org
Background Rapid and effective discrimination between active tuberculosis (ATB) and latent
tuberculosis infection (LTBI) remains a challenge. There is an urgent need for developing …
tuberculosis infection (LTBI) remains a challenge. There is an urgent need for developing …
Biomarkers for discrimination between latent tuberculosis infection and active tuberculosis disease
EJ Won, JH Choi, YN Cho, HM Jin, HJ Kee, YW Park… - Journal of Infection, 2017 - Elsevier
Objective We aimed to determine whether combinations of multiplex cytokine responses
could differentiate Mycobacterium tuberculosis (Mtb) infection states. Methods Mtb-specific …
could differentiate Mycobacterium tuberculosis (Mtb) infection states. Methods Mtb-specific …
[HTML][HTML] Biomarkers on patient T cells diagnose active tuberculosis and monitor treatment response
T Adekambi, CC Ibegbu, S Cagle… - The Journal of …, 2015 - Am Soc Clin Investig
BACKGROUND. The identification and treatment of individuals with tuberculosis (TB) is a
global public health priority. Accurate diagnosis of pulmonary active TB (ATB) disease …
global public health priority. Accurate diagnosis of pulmonary active TB (ATB) disease …
T-cell immunophenotyping distinguishes active from latent tuberculosis
KM Pollock, HS Whitworth… - The Journal of …, 2013 - academic.oup.com
Background. Changes in the phenotype and function of Mycobacterium tuberculosis (M.
tuberculosis)-specific CD4+ and CD8+ T-cell subsets in response to stage of infection may …
tuberculosis)-specific CD4+ and CD8+ T-cell subsets in response to stage of infection may …
[HTML][HTML] Cytometric detection of antigen-specific IFN-γ/IL-2 secreting cells in the diagnosis of tuberculosis
V Sargentini, S Mariotti, S Carrara, MC Gagliardi… - BMC infectious …, 2009 - Springer
Background The purpose of this study was to further characterize the immune response to
Mycobacterium tuberculosis (Mtb) antigens, in order to provide new insight into host …
Mycobacterium tuberculosis (Mtb) antigens, in order to provide new insight into host …
Diagnostic performance of plasma cytokine biosignature combination and MCP-1 as individual biomarkers for differentiating stages Mycobacterium tuberculosis …
J Luo, M Zhang, B Yan, F Li, S Guan, K Chang… - Journal of Infection, 2019 - Elsevier
Objective We aimed to identify plasma cytokine biomarkers that differentiate the infection
stages of Mycobacterium tuberculosis (MTB). Methods This study included a total of 227 …
stages of Mycobacterium tuberculosis (MTB). Methods This study included a total of 227 …