Systemic side effects from ophthalmic timolol and their prevention

FT Fraunfelder, SM Meyer - Journal of Ocular Pharmacology and …, 1987 - liebertpub.com
Topically applied ophthalmic drugs can occasionally produce adverse systemic effects due
to systemic absorption of the drug or impediment of the drug's metabolism. Increasing …

A 7 year prospective comparative study of three topical β blockers in the management of primary open angle glaucoma

PG Watson, MF Barnett, V Parker… - British journal of …, 2001 - bjo.bmj.com
AIM To determine the long term efficacy of monotherapy with topically applied β blocking
agents and to determine whether selective β blockers were able to preserve the visual field …

Long-term betaxolol therapy in glaucoma patients with pulmonary disease

RN Weinreb, R Cherniack, EM van Buskirk… - American journal of …, 1988 - Elsevier
We evaluated the use of topically administered betaxolol 0.5% in 101 glaucoma patients (47
men and 54 women) who had chronic obstructive pulmonary disease, asthma, or timolol …

Topical ophthalmic beta blockers: a comparative review

TJ ZIMMERMAN - Journal of Ocular Pharmacology and …, 1993 - liebertpub.com
Topically administered beta blockers are the preferred medical therapy for glaucoma. These
agents reduce intraocular pressure (IOP), thereby preventing damage to the optic nerve and …

Topical Ophthalmic β‐Adrenergic Blockade for the Treatment of Glaucoma and Ocular Hypertension

WH Frishman, MS Fuksbrumer… - The Journal of Clinical …, 1994 - Wiley Online Library
Since the late 1970s, topical β‐adrenergic blockers have been the drugs of choice in
treating ocular hypertension and associated glaucoma. The currently available drugs are …

A long-term clinical trial of timolol therapy versus no treatment in the management of glaucoma suspects

DL Epstein, JH Krug Jr, E Hertzmark, LL Remis… - Ophthalmology, 1989 - Elsevier
One hundred seven patients with intraocular, pressures (IOPs) between 22 and 28 mmHg
with normal visual fields on Goldmann perimetry and without evidence of optic nerve …

Timolol: a review of its therapeutic efficacy in the topical treatment of glaucoma

RC Heel, RN Brogden, TM Speight, GS Avery - Drugs, 1979 - Springer
Synopsis: Timolol maleate 1 is a nonselective β-blocking drug used for the topical treatment
of increased intraocular pressure in patients with chronic open angle glaucoma. In …

Beta blockers and the elderly with glaucoma: are we adding insult to injury?

E O'Donoghue - The British Journal of Ophthalmology, 1995 - ncbi.nlm.nih.gov
Many elderly people tend not to complain in the face of often serious disease but stoically
accept'every tatter in their mortal dress'l as the inevitable price of aging. We, their carers …

Topical timolol administration reduces the incidence of glaucomatous damage in ocular hypertensive individuals: a randomized, double-masked, long-term clinical …

MA Kass, MO Gordon, MR Hoff… - Archives of …, 1989 - jamanetwork.com
• We conducted a randomized, double-masked, long-term clinical trial to determine whether
topical timolol therapy was effective in delaying or preventing the onset of glaucomatous …

Glaucoma treatment with once-daily levobunolol

T Wandel, AD Charap, RA Lewis, L Partamian… - American journal of …, 1986 - Elsevier
Although twice-daily instillation of topical beta-blockers is the standard regimen for treatment
of increased intraocular pressure, once-daily therapy might improve patient compliance and …