[HTML] nih.gov

[HTML][HTML] Contrast-enhanced ultrasound imaging for the detection of focused ultrasound-induced blood-brain barrier opening

CH Fan, WH Lin, CY Ting, WY Chai, TC Yen, HL Liu… - Theranostics, 2014 - ncbi.nlm.nih.gov
The blood-brain barrier (BBB) can be transiently and locally opened by focused ultrasound
(FUS) in the presence of microbubbles (MBs). Various imaging modalities and contrast …
被引用次数：50 相关文章 所有 12 个版本

Detection of intracerebral hemorrhage and transient blood-supply shortage in focused-ultrasound-induced blood–brain barrier disruption by ultrasound imaging

CH Fan, HL Liu, CY Huang, YJ Ma, TC Yen… - Ultrasound in medicine & …, 2012 - Elsevier
Focused ultrasound (FUS) in the presence of microbubbles can selectively open the blood–
brain barrier (BBB). However, since overexcitation by FUS probably induces intracerebral …
被引用次数：58 相关文章 所有 11 个版本
[PDF] wiley.comFull View

Focused ultrasound microbubble destruction‐mediated changes in blood‐brain barrier permeability assessed by contrast‐enhanced magnetic resonance imaging

F Wang, Y Cheng, J Mei, Y Song… - … of Ultrasound in …, 2009 - Wiley Online Library
Objective. The purpose of this study was to use enhanced magnetic resonance imaging
(MRI) to evaluate the changes of blood‐brain barrier (BBB) permeability in target and …
被引用次数：58 相关文章 所有 4 个版本
[PDF] wiley.comFull View

A quantitative pressure and microbubble‐size dependence study of focused ultrasound‐induced blood‐brain barrier opening reversibility in vivo using MRI

G Samiotaki, F Vlachos, YS Tung… - Magnetic resonance in …, 2012 - Wiley Online Library
Focused ultrasound in conjunction with the systemic administration of microbubbles has
been shown to open the blood‐brain barrier (BBB) selectively, noninvasively and reversibly …
被引用次数：179 相关文章 所有 11 个版本
[HTML] nih.gov

Multi-modality safety assessment of blood-brain barrier opening using focused ultrasound and definity microbubbles: a short-term study

B Baseri, JJ Choi, YS Tung, EE Konofagou - Ultrasound in medicine & …, 2010 - Elsevier
As a potentially viable method of brain drug delivery, the safety profile of blood-brain barrier
(BBB) opening using focused ultrasound (FUS) and ultrasound contrast agents (UCA) needs …
被引用次数：181 相关文章 所有 10 个版本
[HTML] nih.gov

Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index

N McDannold, N Vykhodtseva, K Hynynen - Ultrasound in medicine & …, 2008 - Elsevier
This work investigated the effect of ultrasonic frequency on the threshold for blood-brain
barrier (BBB) disruption induced by ultrasound pulses combined with an ultrasound contrast …
被引用次数：330 相关文章 所有 11 个版本
[HTML] nih.gov

Permeability assessment of the focused ultrasound-induced blood–brain barrier opening using dynamic contrast-enhanced MRI

F Vlachos, YS Tung, EE Konofagou - Physics in Medicine & …, 2010 - iopscience.iop.org
Focused ultrasound (FUS) in conjunction with microbubbles has been shown to successfully
open the blood–brain barrier (BBB) in the mouse brain. In this study, we compute the BBB …
被引用次数：103 相关文章 所有 11 个版本
[HTML] nih.gov

Pharmacokinetic analysis and drug delivery efficiency of the focused ultrasound-induced blood-brain barrier opening in non-human primates

G Samiotaki, ME Karakatsani, A Buch… - Magnetic resonance …, 2017 - Elsevier
Abstract Purpose Focused Ultrasound (FUS) in conjunction with systemically administered
microbubbles has been shown to open the Blood-Brain Barrier (BBB) locally, non-invasively …
被引用次数：37 相关文章 所有 6 个版本
[HTML] umbjournal.org

Microbubble type and distribution dependence of focused ultrasound-induced blood–brain barrier opening

S Wang, G Samiotaki, O Olumolade, JA Feshitan… - Ultrasound in medicine …, 2014 - Elsevier
Focused ultrasound, in the presence of microbubbles, has been used non-invasively to
induce reversible blood–brain barrier (BBB) opening in both rodents and non-human …
被引用次数：107 相关文章 所有 9 个版本
[HTML] sciencedirect.com

[HTML][HTML] Quantitative evaluation of the use of microbubbles with transcranial focused ultrasound on blood–brain-barrier disruption

FY Yang, WM Fu, WS Chen, WL Yeh, WL Lin - Ultrasonics sonochemistry, 2008 - Elsevier
It has been shown that focused ultrasound (FUS) can disrupt the blood–brain barrier (BBB)
noninvasively and reversibly at target locations when applied in the presence of ultrasound …
被引用次数：102 相关文章 所有 11 个版本