Furanocoumarins in anticancer therapy–For and against

J Sumorek-Wiadro, A Zając, A Maciejczyk… - Fitoterapia, 2020 - Elsevier
Furanocoumarins are a class of natural compounds produced by several plants, including
those consumed by humans. They have been used medicinally in eastern countries for …

Anticancer potential of furanocoumarins: mechanistic and therapeutic aspects

S Ahmed, H Khan, M Aschner, H Mirzae… - International Journal of …, 2020 - mdpi.com
Cancer is one of the most extreme medical conditions in both developing and developed
countries around the world, causing millions of deaths each year. Chemotherapy and/or …

Synthetic and natural coumarins as cytotoxic agents

I Kostova - Current Medicinal Chemistry-Anti-Cancer Agents, 2005 - ingentaconnect.com
Coumarins, an old class of compounds, are naturally occurring benzopyrene derivatives. A
lot of coumarins have been identified from natural sources, especially green plants. The …

Furanocoumarins: Biomolecules of therapeutic interest

JA Del Río, L Díaz, D García-Bernal, M Blanquer… - Studies in Natural …, 2014 - Elsevier
Furanocoumarins are a subgroup of phenolic compounds included in the coumarins group.
They can be subdivided into two types: linear, generically known as psoralens, among …

Anticancer activity of natural coumarins for biological targets

A Önder - Studies in Natural Products Chemistry, 2020 - Elsevier
Coumarins are a class of secondary metabolites and naturally occurring benzopyrone
derivatives. Previously, the identification of natural coumarins from natural sources has been …

Natural and synthetic furanocoumarins as treatment for vitiligo and psoriasis

F Conforti, M Marrelli, F Menichini… - Current Drug …, 2009 - ingentaconnect.com
Phototherapy has been used for centuries to treat various skin disorders. Numerous
inflammatory skin diseases, such as atopic dermatitis and pigment disorders like vitiligo and …

Studying plant-derived coumarins for their pharmacological and therapeutic properties as potential anticancer drugs

I Kostova - Expert opinion on drug discovery, 2007 - Taylor & Francis
Coumarins have attracted intense interest in recent years because of their diverse
pharmacological properties. Among these properties, their anticancer effect was most …

Antiproliferative and apoptotic activities of linear furocoumarins from Notopterygium incisum on cancer cell lines

SB Wu, F Pang, Y Wen, HF Zhang, Z Zhao… - Planta medica, 2010 - thieme-connect.com
Bioassay-guided fractionation of the antiproliferative chloroform extract of the traditional
Chinese medicine Qiang-Huo (Notopterygium incisum) led to the isolation of nine linear …

Botanical sources, chemistry, analysis, and biological activity of furanocoumarins of pharmaceutical interest

R Bruni, D Barreca, M Protti, V Brighenti, L Righetti… - Molecules, 2019 - mdpi.com
The aim of this work is to provide a critical review of plant furanocoumarins from different
points of view, including their chemistry and biosynthetic pathways to their extraction …

A review on chemical profile of coumarins and their therapeutic role in the treatment of cancer

K Venkata Sairam, BM Gurupadayya… - Current Drug …, 2016 - ingentaconnect.com
Coumarin class of organic compounds consists of 1, 2-benzopyrone ring system as a basic
parent scaffold. These benzopyrones are subdivided into alpha-benzopyrones and …