Traumatic spinal cord injury exacerbates disability with time due to secondary injury
cascade triggered largely by overproduction of reactive oxygen species (ROS) at the lesion …

High levels of reactive oxygen species (ROS) and inflammation create a complicated
extrinsic neural environment that dominates the initial post‐injury period after spinal cord …

In spinal cord injury (SCI), the initial damage leads to a rapidly escalating cascade of
degenerative events, known as secondary injury. Loss of mitochondrial homeostasis after …

Spinal cord regeneration after a spinal cord injury (SCI) remains a difficult challenge due to
the complicated inflammatory microenvironment and neuronal damage at the injury sites. In …

Spinal cord injury (SCI) and the resulting neurological trauma commonly result in complete
or incomplete neurological dysfunction and there are few effective treatments for primary …

Spinal cord injury (SCI) produces excess reactive oxygen species (ROS) that can
exacerbate secondary injury and lead to permanent functional impairment. Hypothesizing …

Following spinal cord injury (SCI), immune cell infiltration creates an inflammatory and
oxidative microenvironment (known as the secondary injury), which causes neuron death …

Background Traumatic spinal cord injury (SCI) forms a disadvantageous microenvironment
for tissue repair at the lesion site. To consider an appropriate time window for giving a …

Inflammation is a primary component of the central nervous system injury response.
Traumatic brain and spinal cord injury are characterized by a pronounced microglial …

The treatment of spinal cord injury (SCI) remains unsatisfactory owing to the complex
pathophysiological microenvironments at the injury site and the limited regenerative …