In chronic myeloid leukemia (CML) the polymerase chain reaction (PCR) can be used to
detect minimal residual disease after bone marrow transplantation (BMT). Previous studies …

Residual disease remains a major problem in the treatment of human neoplasia. To
effectively monitor minimal leukemic activity after bone marrow transplantation (BMT), we …

Stem cell transplantation (SCT) is an established treatment for various hematological
disorders. Usually, the patient's hematopoiesis is ablated by the combination of the …

Fifteen consecutive patients with Philadelphia chromosome (Ph)‐positive chronic myeloid
leukaemia (CML) who relapsed from T‐cell‐depleted bone marrow transplantation (BMT) …

At present, allogeneic bone marrow transplantation (BMT) seems to be the only curative
treatment for patients with chronic myeloid leukemia (CML). The mechanisms of this …

Hematopoietic chimerism as a predictive marker for the relapse of acute leukemia after
allogeneic BMT was evaluated in a prospective study. Monthly assays of hematopoietic …

We have used a new single‐step real‐time reverse transcription polymerase chain reaction
(RT‐PCR) method to quantify BCR‐ABL transcripts, thereby estimating the relapse stage in …

Serial cytogenetic studies were performed on 64 patients with chronic myelogenous
leukemia (CML) after T cell-depleted allogeneic bone marrow transplantation (BMT). Forty …

Recently, we have shown that patients with acute leukaemias and myelodysplastic
syndromes (MDS), who showed increasing mixed chimaerism (MC) upon serial PCR …

To evaluate the remission quality of Philadelphia chromosome (Ph)-positive, BCR/ABL-
positive CML patients after allogeneic bone marrow transplantation (BMT) we used the …