VE-cadherin: at the front, center, and sides of endothelial cell organization and function

ES Harris, WJ Nelson - Current opinion in cell biology, 2010 - Elsevier
Endothelial cells form cell–cell adhesive structures, called adherens and tight junctions,
which maintain tissue integrity, but must be dynamic for leukocyte transmigration during the …

VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation

D Vestweber - Arteriosclerosis, thrombosis, and vascular biology, 2008 - Am Heart Assoc
Vascular endothelial (VE)-cadherin is a strictly endothelial specific adhesion molecule
located at junctions between endothelial cells. In analogy of the role of E-cadherin as major …

The role of VE-cadherin in vascular morphogenesis and permeability control

E Dejana, D Vestweber - Progress in molecular biology and translational …, 2013 - Elsevier
VE-cadherin is an endothelial-specific cadherin that is essential for the formation and
regulation of endothelial cell junctions. The adhesive function and expression levels of VE …

VE-cadherin and endothelial adherens junctions: active guardians of vascular integrity

M Giannotta, M Trani, E Dejana - Developmental cell, 2013 - cell.com
VE-cadherin is a component of endothelial cell-to-cell adherens junctions, and it has a key
role in the maintenance of vascular integrity. During embryo development, VE-cadherin is …

Endothelial permeability and VE-cadherin: a wacky comradeship

J Gavard - Cell adhesion & migration, 2013 - Taylor & Francis
The endothelium forms a selective semi-permeable barrier controlling bidirectional transfer
between blood vessel and irrigated tissues. This crucial function relies on the dynamic …

VE-cadherin in vascular development: a coordinator of cell signaling and tissue morphogenesis

AK Lagendijk, BM Hogan - Current topics in developmental biology, 2015 - Elsevier
Blood and lymphatic vessels make up the vascular system of vertebrates and are lined by
specialized endothelial cells. The connections between endothelial cells are formed by …

[HTML][HTML] Breaking the VE-cadherin bonds

J Gavard - FEBS letters, 2009 - Elsevier
Exchanges between the blood compartment and the surrounding tissues require a tight
regulation by the endothelial barrier. Recent reports inferred that VE-cadherin, an …

Vascular endothelial (VE)-cadherin: only an intercellular glue?

E Dejana, G Bazzoni, MG Lampugnani - Experimental cell research, 1999 - Elsevier
Data collected during the past years indicate that AJ-and more specifically VE-cadherin play
an important role in endothelial cell biology. VE-cadherin may transfer information …

VE‐cadherin is a critical endothelial regulator of TGF‐β signalling

N Rudini, A Felici, C Giampietro… - The EMBO …, 2008 - embopress.org
VE‐cadherin is an endothelial‐specific transmembrane protein concentrated at cell‐to‐cell
adherens junctions. Besides promoting cell adhesion and controlling vascular permeability …

The role of adherens junctions and VE-cadherin in the control of vascular permeability

E Dejana, F Orsenigo… - Journal of cell …, 2008 - journals.biologists.com
Endothelial cells control the passage of plasma constituents and circulating cells from blood
to the underlying tissues. This specialized function is lost or impaired in several pathological …