[HTML][HTML] Copper oxide nanoparticle toxicity profiling using untargeted metabolomics
MSP Boyles, C Ranninger, R Reischl, M Rurik… - Particle and fibre …, 2015 - Springer
Background The rapidly increasing number of engineered nanoparticles (NPs), and
products containing NPs, raises concerns for human exposure and safety. With this …
products containing NPs, raises concerns for human exposure and safety. With this …
Predictive metabolomic signatures for safety assessment of metal oxide nanoparticles
The widespread use of metal oxide nanoparticles (MOx NPs) poses a risk of exposure that
may lead to adverse health effects on humans. Even though a number of toxicological …
may lead to adverse health effects on humans. Even though a number of toxicological …
Metabolomics profiling to investigate nanomaterial toxicity in vitro and in vivo
A Bannuscher, B Hellack, A Bahl, J Laloy… - …, 2020 - Taylor & Francis
Nanomaterials (NMs) can be produced in plenty of variants posing several challenges for
NM hazard and risk assessment. Metabolomic profiling of NM-treated cells and tissues …
NM hazard and risk assessment. Metabolomic profiling of NM-treated cells and tissues …
Metabolomics techniques for nanotoxicity investigations
M Lv, W Huang, Z Chen, H Jiang, J Chen, Y Tian… - Bioanalysis, 2015 - Future Science
Nanomaterials are commonly defined as engineered structures with at least one dimension
of 100 nm or less. Investigations of their potential toxicological impact on biological systems …
of 100 nm or less. Investigations of their potential toxicological impact on biological systems …
Lipidomics reveals insights on the biological effects of copper oxide nanoparticles in a human colon carcinoma cell line
NGC Soria, DS Aga, GE Atilla-Gokcumen - Molecular Omics, 2019 - pubs.rsc.org
Engineered nanomaterials have unique properties compared to their bulk counterparts.
Copper oxide nanoparticles (CuO NPs) are one example of nanomaterials used in a wide …
Copper oxide nanoparticles (CuO NPs) are one example of nanomaterials used in a wide …
[HTML][HTML] Integration of metabolomics and transcriptomics in nanotoxicity studies
TH Shin, HS Lee, HJ Park, MS Jin, MJ Paik… - BMB …, 2018 - ncbi.nlm.nih.gov
Biomedical research involving nanoparticles has produced useful products with medical
applications. However, the potential toxicity of nanoparticles in biofluids, cells, tissues, and …
applications. However, the potential toxicity of nanoparticles in biofluids, cells, tissues, and …
Impact of copper oxide particle dissolution on lung epithelial cell toxicity: response characterization using global transcriptional analysis
A Boyadzhiev, ML Avramescu, D Wu, A Williams… - …, 2021 - Taylor & Francis
The in vitro and in vivo toxicity of copper oxide nanoparticles (CuO NPs) is attributed to both
particle and dissolved copper ion species. However, a clear understanding of (1) the specific …
particle and dissolved copper ion species. However, a clear understanding of (1) the specific …
Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short‐term inhalation exposure to copper oxide …
PM Costa, I Gosens, A Williams, L Farcal… - Journal of applied …, 2018 - Wiley Online Library
Our recent studies revealed a dose‐dependent proinflammatory response to copper oxide
nanoparticles (CuO NPs) in rats following short‐term inhalation exposure for five …
nanoparticles (CuO NPs) in rats following short‐term inhalation exposure for five …
Copper oxide nanoparticles: In vitro and in vivo toxicity, mechanisms of action and factors influencing their toxicology
Abstract Copper oxide nanoparticles (CuO NPs) have received increasing interest due to
their distinctive properties, including small particle size, high surface area, and reactivity …
their distinctive properties, including small particle size, high surface area, and reactivity …
Metabolomics techniques in nanotoxicology studies
LK Schnackenberg, J Sun, RD Beger - Nanotoxicity: Methods and …, 2012 - Springer
The rapid growth in the development of nanoparticles for uses in a variety of applications
including targeted drug delivery, cancer therapy, imaging, and as biological sensors has led …
including targeted drug delivery, cancer therapy, imaging, and as biological sensors has led …