[HTML][HTML] Phase I/II study of immunotherapy using tumor antigen-pulsed dendritic cells in patients with hepatocellular carcinoma

F Tada, M Abe, M Hirooka, Y Ikeda… - International …, 2012 - spandidos-publications.com
Dendritic cells (DCs) are increasingly used as adjuvants for vaccination strategies; however,
there has been very little development in DC vaccines for patients with hepatocellular …

[HTML][HTML] Immune response, safety, and survival and quality of life outcomes for advanced colorectal cancer patients treated with dendritic cell vaccine and cytokine …

H Zhu, X Yang, J Li, Y Ren, T Zhang, C Zhang… - BioMed research …, 2014 - hindawi.com
Purpose. To determine the immune response after dendritic cell (DC) vaccine and cytokine-
induced killer cells (CIK) therapy and assess its associated toxicity, survival benefit, and …

Dendritic cell vaccine therapy for colorectal cancer

AL Wooster, LH Girgis, H Brazeale, TS Anderson… - Pharmacological …, 2021 - Elsevier
Colorectal cancer (CRC) remains a leading cause of cancer-related deaths in the United
States despite an array of available treatment options. Current standard-of-care …

Chemotherapy combined with dendritic cell vaccine and cytokine-induced killer cells in the treatment of colorectal carcinoma: a meta-analysis

X Zhou, X Mo, J Qiu, J Zhao, S Wang… - Cancer management …, 2018 - Taylor & Francis
Aim To investigate the efficacy and safety of dendritic cell (DC) vaccine combined with
cytokine-induced killer (CIK) cell therapy in colorectal carcinoma (CRC). Patients and …

Phase I study of immunization with dendritic cells (DC) modified with recombinant fowlpox encoding carcinoembryonic antigen (CEA) and the triad of costimulatory …

M Morse, T Clay, A Hobeika, T Osada… - Journal of Clinical …, 2004 - ascopubs.org
2508 Background: We hypothesize that the activity of vaccines based on DC loaded with
tumor antigens will be enhanced by modifications that increase antigen expression and …

Efficient activation of autologous tumor-specific T cells: a simple coculture technique of autologous dendritic cells compared to established cell fusion strategies in …

A Draube, M Beyer, S Schumer… - Journal of …, 2007 - journals.lww.com
Different technologies have been employed to deliver the whole spectrum of tumor antigens
(TAs) to dendritic cells (DCs) to be presented to T cells. These include whole tumor RNA …

Current status of dendritic cell-based tumor vaccination

J Dannull, T Cerny, DK Ackermann… - Oncology Research and …, 2000 - karger.com
For several decades, approaches utilizing nonspecific immune stimulants have provided
evidence that the immune system, when properly activated, may eradicate cancer cells …

[PDF][PDF] Dendritic cell vaccine and its application in cancer therapy

BS Farashi, N Khansari - Int J Vaccines Vaccin, 2015 - academia.edu
Dendritic cells (DCs) are the most potent antigens presenting cells in the immune system.
They have a high capacity to trigger antigen-specific immune responses and promote both …

[HTML][HTML] Heat-shocked tumor cell lysate-pulsed dendritic cells induce effective anti-tumor immune response in vivo

J Qiu, GW Li, YF Sui, HP Song, SY Si… - World journal of …, 2006 - ncbi.nlm.nih.gov
AIM: To study whether heat-shocked tumor cells could enhance the effect of tumor cell lysate-
pulsed dendritic cells (DCs) in evoking anti-tumor immune response in vivo. METHODS …

Dendritic cell-based cancer immunotherapy

EG Engleman - Seminars in oncology, 2003 - Elsevier
The development of effective cancer vaccines depends heavily on the ability to deliver target
antigens to generate an immune response. Dendritic cells are the most potent antigen …