A. INTRODUCTION Medicinal chemists today find themselves in an increasingly information-
rich environment. An abundance of compound activity and affinity data is being published …

The last two years have seen a dramatic expansion in public cheminformatics, as
exemplified by the approximate five-fold growth of PubChem from over 50 contributing data …

Various biological, chemical and bibliographic databases have grown tremendously in
recent years with respect to both their diversity and size. In many cases, these databases …

Public domain repositories of compound structures and activity data are indispensable tools
for many aspects of pharmaceutical research, especially in academic environments. Such …

There was a time, in the not-too-distant past, where pharmaceutical companies often had the
edge over academic research in the drug discovery field, in part for a simple but powerful …

PubChem is a public chemical database that provides information for more than 110 million
compounds, collected from hundreds of data sources. A wide variety of chemical information …

Within the last decade open data concepts has been gaining increasing interest in the area
of drug discovery. With the launch of ChEMBL and PubChem, an enormous amount of …

Large libraries of chemical compounds reflect the exponentially growing data-enrichment in
drug discovery that trends towards fully automated informatics solutions to study structure …

Background Since 2004 public cheminformatic databases and their collective functionality
for exploring relationships between compounds, protein sequences, literature and assay …

NEWS & ANALYSIS Page 1 © 2006 Nature Publishing Group Monya Baker In terms of freely
available resources chemists have long been green with envy with what is available to …