Fertilization failures diminish the number of zygotes available for fertility treatment. When
considering the potential etiologies of fertilization failures, oocyte determinants merit careful …

BACKGROUND The complexity of fertilization failure during assisted reproductive
technologies (ART) is often under-appreciated, as this failure can occur at any number of …

Oocyte quality impacts early embryonic survival and the establishment and maintenance of
pregnancy. Although meiosis may be completed successfully, there are a variety of other …

Assessing the quality of oocytes derived from in vitro maturation: are we looking under the
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Embryonic development is readily compromised by imperfections introduced during the
process of oocyte maturation. We discuss the nature and causes of these imperfections …

Infertility is described as unexplained when pregnancy does not occur despite ovulation,
patent Fallopian tubes, and normal semen parameters. Oocyte developmental competence …

The female gamete plays a crucial role in determining embryo competence and therefore in
vitro fertilization (IVF) results. Oocyte quality is not only influenced by the nuclear and …

It is obvious that both oocyte and sperm quality play a major role in the success of in vitro
fertilization (IVF). In the case of total fertilization failure (TFF), and mainly for idiopathic …

The metaphase II (MII) oocyte is the mature female gamete, produced from a complex
maturation process called oogenesis that starts in the first weeks of embryogenesis in the …

One of the great challenges in reproductive medicine today is the management of cases with
poor-quality oocytes, a problem compounded by the falling ovarian reserve towards …