The effect of topical ophthalmic instillation of timolol and betaxolol on lung function in asthmatic subjects

TL Dunn, MJ Gerber, AS Shen… - American Review of …, 1986 - atsjournals.org
The propensity of systemic beta-adrenergic blockers to cause bronchoconstriction in
patients with reactive airway disease is well recognized. A study was carried out to …

Effects of topical betaxolol, timolol, and placebo on pulmonary function in asthmatic bronchitis

RB Schoene, RNT Abuan, RL Ward… - American journal of …, 1984 - Elsevier
To evaluate the effects of two beta-adrenergic blocking agents on cardiopulmonary function,
we investigated two topical ophthalmologic preparations, betaxolol 1% and timolol 0.5%, in …

Betaxolol in patients with glaucoma and asthma

EM Van Buskirk, RN Weinreb, DP Berry… - American journal of …, 1986 - Elsevier
We evaluated the use of topically administered betaxolol, a cardioselective beta-adrenergic
blocking agent, in 11 patients (eight women and three men, 40 to 81 years old) who had …

Pulmonary effects of topical timolol

NB Charan, S Lakshminarayan - Archives of Internal Medicine, 1980 - jamanetwork.com
Timolol, a β-adrenergic blocking agent, recently became available for the treatment of
glaucoma. We report the occurrence of acute bronchospasm in a previously asymptomatic …

Timolol eyedrop‐induced severe bronchospasm

S Laursen, P Bjerrum - Acta Medica Scandinavica, 1982 - Wiley Online Library
A patient with glaucoma simplex and chronic pulmonary obstruction was treated with the
non‐selective β‐adrenergic blocking agent timolol in ophthalmic solution of 0.25% for 1 1/2 …

Comparison of the airway response to eye drops of timolol and its isomer L‐714,465 in asthmatic subjects.

R Richards, AE Tattersfield - British journal of clinical …, 1987 - Wiley Online Library
1. The inadvertent administration of timolol to asthmatic patients continues to cause
occasional severe and even fatal attacks of asthma. The (R)‐enantiomer of timolol, L …

Long-term betaxolol therapy in glaucoma patients with pulmonary disease

RN Weinreb, R Cherniack, EM van Buskirk… - American journal of …, 1988 - Elsevier
We evaluated the use of topically administered betaxolol 0.5% in 101 glaucoma patients (47
men and 54 women) who had chronic obstructive pulmonary disease, asthma, or timolol …

Bronchial and cardiovascular effects of ocular topical B-antagonists in asthmatic subjects: comparison of timolol, carteolol, and metipranolol.

CL Le Jeunne, FC Hugues, JL Dufier… - Journal of clinical …, 1989 - europepmc.org
B antagonists eye drops are most effective for the treatment of chronic open angle
glaucoma. By this way of administration they have a very good systemic bioavailability …

Unsuspected Bronchospasm in Association with Topical Timolola Common Problem in Elderly People: Can We easily identify Those affected and do Cardioselective …

P Diggory, P Heyworth, G Chau, S McKENZIE… - Age and …, 1994 - academic.oup.com
The extent of impairment of respiratory function in a group of 52 elderly, glaucomatous
patients receiving topical timolol therapy was investigated. To predict those patients who …

Improved lung function tests on changing from topical timolol: non-selective beta-blockade impairs lung function tests in elderly patients

P Diggory, P Heyworth, G Chau, S McKenzie… - Eye, 1993 - nature.com
Fifty-two elderly glaucomatous patients, without a history of asthma or obstructive airways
disease, who were using topical timolol for control of intraocular pressure were recruited …