Influence of cardioselectivity and respiratory disease on pulmonary responsiveness to beta-blockade

HW Clague, D Ahmad, SG Carruthers - European journal of clinical …, 1984 - Springer
The effects on ventilation of the non-selective beta-blocker propranolol, and the relatively
cardioselective beta-blocker, metoprolol, were compared in a randomized single-blind …

Respiratory tolerance of bisoprolol and metoprolol in asthmatic patients

JWJ Lammers, HTM Folgering… - Journal of …, 1986 - journals.lww.com
The respiratory tolerance of the [beta] 1-adrenoceptor-selective blockers bisoprolol and
metoprolol was investigated in eight male asthmatic patients. The interaction with the …

Adverse Pulmonary Effects of Topical β Blockers Used in the Treatment of Glaucoma

J Avorn, RJ Glynn, JH Gurwitz, RL Bohn… - Journal of …, 1993 - journals.lww.com
We conducted a case-control study to measure the risk of pulmonary side effects following
the use of topical glaucoma medications, particularly the [beta] blockers, and to identify …

Timolol: a review of its therapeutic efficacy in the topical treatment of glaucoma

RC Heel, RN Brogden, TM Speight, GS Avery - Drugs, 1979 - Springer
Synopsis: Timolol maleate 1 is a nonselective β-blocking drug used for the topical treatment
of increased intraocular pressure in patients with chronic open angle glaucoma. In …

Exacerbation of bronchorrhea induced by topical timolol

CA Guzman - American Review of Respiratory Disease, 1980 - atsjournals.org
7. They are not convinced of the value of applying a runs test to the data to assess the
adequacy of fit and they imply that this may actually be misleading. There seems to be some …

Effect of β-blocker therapy on airway function

AE Tattersfield, RN Harrison - Drugs, 1983 - Springer
The ability of β-blockers to cause bronchoconstriction in asthmatic patients is related to their
degree of cardioselectivity. The assessment of cardioselectivity in animals should be …

ß1‐ and ß2‐antagonist activity of topically applied betaxolol and timolol in the systemic circulation

ML Vuori, T Ali‐Melkkilä, T Kaila, E Lisalo… - Acta …, 1993 - Wiley Online Library
The ß1‐and ß2‐antagonist activity of betaxolol and timolol in the systemic circulation was
studied ex‐vivo after their ocular administration in thirty patients during cataract surgery. The …

Comparison of respiratory effects of two cardioselective beta-blockers, celiprolol and atenolol, in asthmatics with mild to moderate hypertension

AI van Zyl, AA Jennings, ED Bateman, LH Opie - Chest, 1989 - Elsevier
The effects of two cardioselective beta-adrenergic blocking agents—celiprolol (claimed to
have bronchodilator properties) and atenolol (without such claims)—on respiratory function …

Betaxolol and timolol: a comparison of efficacy and side effects

DP Berry, EM Van Buskirk… - Archives of …, 1984 - jamanetwork.com
• Betaxolol hydrochloride, 0.5%, and timolol maleate, 0.5%, were compared in a 26-week
randomized, double-masked study involving 46 patients with primary open-angle glaucoma …

Bronchial beta‐adrenoceptor blockade following eyedrops of timolol and its isomer L‐714,465 in normal subjects.

R Richards, AE Tattersfield - British Journal of Clinical …, 1985 - Wiley Online Library
The R‐enantiomer of timolol, L‐714,465, is considerably less potent as a beta 1‐and beta 2‐
adrenoceptor antagonist in animals than timolol, whilst only slightly less potent in reducing …