Topical timolol given for the treatment or chronic simple glaucoma may cause unrecognised
bronchospasm among elderly people. We recruited 80 patients aged over 60 years, who …

Timolol maleate is a non‐selective β‐adrenoceptor antagonist currently used mainly as an
ocular preparation for the treatment of glaucoma and ocular hypertension. Despite the …

We designed this investigation to assess the occurrence of systemic beta adrenergic side
effects associated with the inhalation of an increased dose of the beta 2 receptor agonist …

Eight asthmatic patients were investigated in a double-blind cross-over study after oral
administration of 100 mg atenolol, 10 mg metoprolol and placebo. Four increasing doses of …

We studied cardiovascular effects related to ophthalmic timolol maleate, a beta-adrenergic
blocker commonly used to treat chronic glaucoma. Twenty normal subjects were randomly …

PURPOSE: In addition to their bronchodilatory effects, β2-agonists protect against
bronchoconstriction, such as that caused by methacholine challenge. However …

The β 2-adrenoceptor mediated effects on ventilatory capacity, forced expiratory volume in
one second (FEV 1), forced ventilatory capacity (FVC), heart rate, and skeletal muscle tremor …

The effects on lung function of labetalol (a combined α and β adrenergic receptor blocker)
and three β adrenergic receptor blockers (propranolol, atenolol, metoprolol) have been …

Studies in asthmatic subjects have shown that propranolol markedly reduces the one-
second forced expired volume. By using sensitive, body plethysmographic methods, airway …

Since the introduction of β-adrenergic receptor blocking (β-blocking) drugs there have been
numerous reports of their producing severe bronchospasm in asthmatic patients. Further …