Integrative Multi-Omics Approaches for Identifying Cervical Cancer Therapeutic Targets

SK Duppala, R Yadala, A Velingkar, P Suravajhala… - bioRxiv, 2022 - biorxiv.org
After breast cancer, cervical cancer (CC) is one of the most common malignancies in women
globally. Over 90% of chronic infections are caused by human papillomavirus (HPV) and its …

[HTML][HTML] Exploration of biomarkers for the diagnosis, treatment and prognosis of cervical cancer: a review

M Arip, LF Tan, R Jayaraj, M Abdullah, M Rajagopal… - Discover Oncology, 2022 - Springer
As the fourth most diagnosed cancer, cervical cancer (CC) is one of the major causes of
cancer-related mortality affecting females globally, particularly when diagnosed at advanced …

[HTML][HTML] Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective

M Kori, K Yalcin Arga - PLoS One, 2018 - journals.plos.org
The malignant neoplasm of the cervix, cervical cancer, has effects on the reproductive tract.
Although infection with oncogenic human papillomavirus is essential for cervical cancer …

[HTML][HTML] Integrative systems biology approaches to identify potential biomarkers and pathways of cervical cancer

AR Oany, M Mia, T Pervin, SA Alyami… - Journal of personalized …, 2021 - mdpi.com
Nowadays, cervical cancer (CC) is treated as the leading cancer among women throughout
the world. Despite effective vaccination and improved surgery and treatment, CC retains its …

Novel genomic biomarker candidates for cervical cancer as identified by differential co-expression network analysis

M Kori, E Gov, KY Arga - Omics: a journal of integrative biology, 2019 - liebertpub.com
Cervical cancer is the second most common malignancy and the third reason for mortality
among women in developing countries. Although infection by the oncogenic human …

[HTML][HTML] Identification of Core Genes Involved in the Progression of Cervical Cancer Using an Integrative mRNA Analysis

M Dudea-Simon, D Mihu, A Irimie… - International journal of …, 2020 - mdpi.com
In spite of being a preventable disease, cervical cancer (CC) remains at high incidence, and
it has a significant mortality rate. Although hijacking of the host cellular pathway is …

[HTML][HTML] Multidimensional outlook on the pathophysiology of cervical cancer invasion and metastasis

N George, P Bhandari, P Shruptha, P Jayaram… - Molecular and Cellular …, 2023 - Springer
Cervical cancer being one of the primary causes of high mortality rates among women is an
area of concern, especially with ineffective treatment strategies. Extensive studies are …

Interplay of miR-542, miR-126, miR-143 and miR-26b with PI3K-Akt is a Diagnostic Signal and Putative Regulatory Target in HPV-Positive Cervical Cancer

A Rahimi-Moghaddam, N Ghorbanmehr, S Gharbi… - Biochemical …, 2024 - Springer
Abstract Human papillomavirus accounts for 99.7% of all cervical cancer cases worldwide.
The viral oncoproteins alter normal cell signaling and gene expression, resulting in loss of …

[HTML][HTML] Understanding cervical cancer through proteomics

F Martínez-Rodríguez, JE Limones-González… - Cells, 2021 - mdpi.com
Cancer is one of the leading public health issues worldwide, and the number of cancer
patients increases every day. Particularly, cervical cancer (CC) is still the second leading …

[HTML][HTML] Deciphering cervical cancer-associated biomarkers by integrated multi-omics approach

X Li, MA Abdel-Maksoud, I Iqbal… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objectives: Cervical Squamous Cell Carcinoma (CESC) is one of the most fatal female
malignancies, and the underlying molecular mechanisms governing this disease have not …