This book provides an overview of the scientific methods used to search, analyse, appraise
and synthesize studies on angiogenesis. It is intended to serve as a comprehensive piece of …

This volume addresses current emerging concepts in the field of angiogenesis, including
important angiogenesis modifiers which are essential in combination with growth factors …

I would like to dedicate this book to my parents, my sister and brother, and my family for their
unconditional love and support and to the love of my life for being my soul mate, my partner …

The cardiovascular system is the first functional organ system to develop in the vertebrate
embryo.[1] Blood vessels nourish organs with vital nutrients and oxygen and, thus, new …

The therapeutic potential of targeting tumor endothelium and vascular supply is now widely
recognized to treat different diseases. One such disease is cancer; where endothelial cells …

Angiogenesis—the process of new blood-vessel growth—has an essential role in
development, reproduction and repair. However, pathological angiogenesis occurs not only …

Angiogenesis is the growth of new vessels from pre-existing blood vessels. Angiogenesis is
critical during embryogenesis but occurs minimally in healthy adults, except in wound repair …

Tissue homeostasis is dependent upon an adequate supply of oxygen and nutrients
delivered through blood vessels. Since the cells must be located within 100-200 μm of blood …

The field of antiangiogenesis has shown a remarkably rapid evolution from the discovery at
the bench to translation into the clinic. Currently a wide variety of compounds are in clinical …

The induction of neoangiogenesis is a critical step already present at the early stages of
tumor development and dissemination. The progressive identification of molecules playing a …