Circular RNAs play roles in regulatory networks of cell signaling pathways in human cancers

M Almouh, E Razmara, A Bitaraf, MH Ghazimoradi… - Life Sciences, 2022 - Elsevier
Abstract Aims Circular RNAs (circRNAs) are endogenous covalently closed non-coding
RNAs produced by reverse splicing of linear RNA. These molecules are highly expressed in …

Circular RNAs: emerging cancer biomarkers and targets

Y Zhang, W Liang, P Zhang, J Chen, H Qian… - Journal of Experimental …, 2017 - Springer
CircRNAs are a class of RNA molecules that structurally form closed loops. CircRNAs are
abundant in eukaryotic transcripts and show certain levels of tissue and cell specificity …

[HTML][HTML] Circular RNAs: implications of signaling pathways and bioinformatics in human cancer

F Hu, Y Peng, X Fan, X Zhang, Z Jin - Cancer Biology & Medicine, 2023 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) form a class of endogenous single-stranded RNA transcripts that
are widely expressed in eukaryotic cells. These RNAs mediate post-transcriptional control of …

Circular RNAs: emerging regulators of the major signaling pathways involved in cancer progression

M Papatsirou, PI Artemaki, P Karousi, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) are single-stranded RNA molecules that form a
covalently closed loop structure. They are characterized by distinct features and …

Circular RNAs: emerging role in cancer diagnostics and therapeutics

A Rajappa, S Banerjee, V Sharma… - Frontiers in molecular …, 2020 - frontiersin.org
Circular RNAs (circRNAs) are rapidly coming to the fore as major regulators of gene
expression and cellular functions. They elicit their influence via a plethora of diverse …

Circular RNAs modulate cancer hallmark and molecular pathways to support cancer progression and metastasis

AA Yarmishyn, AA Ishola, CY Chen, ND Verusingam… - Cancers, 2022 - mdpi.com
Simple Summary Circular RNAs (circRNA) are a type of RNA molecule of circular shape that
are now being extensively studied due to the important roles they play in different biological …

Circular RNAs as biomarkers and therapeutic targets in cancer

A Beilerli, I Gareev, O Beylerli, G Yang, V Pavlov… - Seminars in cancer …, 2022 - Elsevier
Circular RNAs (circRNAs) are a class of single-stranded closed non-coding RNA molecules
(ncRNAs), which are formed as a result of reverse splicing of mRNAs. Despite their relative …

Circular RNAs regulate parental gene expression: A new direction for molecular oncology research

H Wang, X Gao, S Yu, W Wang, G Liu, X Jiang… - Frontiers in …, 2022 - frontiersin.org
CircRNAs have been the focus of research in recent years. They are differentially expressed
in various human tumors and can regulate oncogenes and tumor suppressor genes …

Circular RNAs: An emerging type of RNA in cancer

LD Hou, J Zhang - International journal of immunopathology …, 2017 - journals.sagepub.com
Circular RNAs (circRNAs), a novel type of widespread and diverse endogenous non-coding
RNAs (ncRNAs), which are different from the linear RNAs, form a covalently closed …

Regulatory effects of circular RNAs on host genes in human cancer

X Wang, H Li, Y Lu, L Cheng - Frontiers in oncology, 2021 - frontiersin.org
Circular RNAs (circRNAs) are a class of single-stranded, covalent closed-loop RNAs with
tissue-/development-specific expression patterns. circRNAs are stable and play oncogenic …