Interleukin-1 receptor antagonist, a biomarker of response to anti-TB treatment in HIV/TB co-infected patients

J Nouhin, P Pean, Y Madec, MF Chevalier, C Didier… - Journal of Infection, 2017 - Elsevier
Objectives Despite the high frequency of tuberculosis-associated immune reconstitution
inflammatory syndrome (TB-IRIS) in human immunodeficiency virus (HIV)/TB co-infected …

Lower pre-treatment T cell activation in early-and late-onset tuberculosis-associated immune reconstitution inflammatory syndrome

O Goovaerts, W Jennes, M Massinga-Loembé… - PloS one, 2015 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an inflammatory complication in HIV-TB co-infected patients receiving antiretroviral …

Antigen-specific interferon-gamma responses and innate cytokine balance in TB-IRIS

O Goovaerts, W Jennes, M Massinga-Loembe… - PLoS …, 2014 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) remains a poorly understood complication in HIV-TB patients receiving antiretroviral …

Biomarkers of CD4+ T-cell activation as risk factors for tuberculosis-associated immune reconstitution inflammatory syndrome

LA Chakrabarti, C Boucherie, F Bugault, MC Cumont… - Aids, 2014 - journals.lww.com
Objective: Patients coinfected with HIV and Mycobacterium tuberculosis frequently
experience a paradoxical worsening of tuberculosis (TB) symptoms early after the initiation …

TB-IRIS, T-cell activation, and remodeling of the T-cell compartment in highly immunosuppressed HIV-infected patients with TB

V Haridas, P Pean, LD Jasenosky, Y Madec… - Aids, 2015 - journals.lww.com
Objective: To investigate the impact of tuberculosis-associated immune reconstitution
inflammatory syndrome (TB-IRIS) upon immunological recovery and the T-cell compartment …

Circulating inflammatory biomarkers can predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome

LJ Haddow, O Dibben, MYS Moosa, P Borrow… - Aids, 2011 - journals.lww.com
Objective: To identify inflammatory biomarker profiles during paradoxical and unmasking
tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS), and …

Increased KLRG1 and PD-1 expression on CD8 T lymphocytes in TB-IRIS

O Goovaerts, M Massinga-Loembe, P Ondoa… - PLoS …, 2019 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an inflammatory complication in HIV-TB co-infected patients receiving antiretroviral …

LPS-binding protein and IL-6 mark paradoxical tuberculosis immune reconstitution inflammatory syndrome in HIV patients

O Goovaerts, W Jennes, M Massinga-Loembé… - PloS one, 2013 - journals.plos.org
Background Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) remains a poorly understood complication in HIV-TB co-infected patients initiating …

The tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS)

I Sereti, GP Bisson, G Meintjes - HIV and Tuberculosis: A Formidable …, 2019 - Springer
Initiation of antiretroviral therapy (ART) in HIV infected people with tuberculosis (TB)
significantly improves their overall prognosis, but paradoxical worsening of the clinical or …

Plasma interleukin-18 levels are a biomarker of innate immune responses that predict and characterize tuberculosis-associated immune reconstitution inflammatory …

HY Tan, YK Yong, BB Andrade, EM Shankar… - Aids, 2015 - journals.lww.com
Background: Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is a substantial problem in HIV/TB coinfected patients commencing antiretroviral …