[HTML][HTML] Complement analysis 2016: Clinical indications, laboratory diagnostics and quality control
Z Prohászka, B Nilsson, A Frazer-Abel, M Kirschfink - Immunobiology, 2016 - Elsevier
In recent years, complement analysis of body fluids and biopsies, going far beyond C3 and
C4, has significantly enhanced our understanding of the disease process. Such expanded …
C4, has significantly enhanced our understanding of the disease process. Such expanded …
[HTML][HTML] Expanding horizons in complement analysis and quality control
A Frazer-Abel, M Kirschfink, Z Prohászka - Frontiers in immunology, 2021 - frontiersin.org
Complement not only plays a key role in host microbial defense but also modulates the
adaptive immune response through modification of T-and B-cell reactivity. Moreover, a …
adaptive immune response through modification of T-and B-cell reactivity. Moreover, a …
[HTML][HTML] Interpretation of serological complement biomarkers in disease
Complement system aberrations have been identified as pathophysiological mechanisms in
a number of diseases and pathological conditions either directly or indirectly. Examples of …
a number of diseases and pathological conditions either directly or indirectly. Examples of …
[HTML][HTML] Pitfalls in complement analysis: A systematic literature review of assessing complement activation
RJ Brandwijk, MAHM Michels, M van Rossum… - Frontiers in …, 2022 - frontiersin.org
Background The complement system is an essential component of our innate defense and
plays a vital role in the pathogenesis of many diseases. Assessment of complement …
plays a vital role in the pathogenesis of many diseases. Assessment of complement …
Complement analysis in the era of targeted therapeutics
Z Prohászka, M Kirschfink, A Frazer-Abel - Molecular immunology, 2018 - Elsevier
Complement immunobiology, and with it complement analysis, has undergone a
renaissance in the past decade. Classically, complement analysis was limited number of …
renaissance in the past decade. Classically, complement analysis was limited number of …
Clinical complement analysis—an overview
L Skattum - Transfusion Medicine Reviews, 2019 - Elsevier
The complement system plays an important role in varying types of disease, ranging from
inflammatory and autoimmune disorders to immune deficiency states. In addition, new …
inflammatory and autoimmune disorders to immune deficiency states. In addition, new …
Complement diagnostics: concepts, indications, and practical guidelines
Aberrations in the complement system have been shown to be direct or indirect
pathophysiological mechanisms in a number of diseases and pathological conditions such …
pathophysiological mechanisms in a number of diseases and pathological conditions such …
Complement analysis in the 21st century
TE Mollnes, TS Jokiranta, L Truedsson, B Nilsson… - Molecular …, 2007 - Elsevier
Complement analysis in the clinic is usually associated with the quantification of C3 and C4,
measurement of C1-inhibitor and screening for complement activity. These analyses have …
measurement of C1-inhibitor and screening for complement activity. These analyses have …
[HTML][HTML] Complementopathies and precision medicine
E Gavriilaki, RA Brodsky - The Journal of clinical …, 2020 - Am Soc Clin Investig
The renaissance of complement diagnostics and therapeutics has introduced precision
medicine into a widened field of complement-mediated diseases. In particular, complement …
medicine into a widened field of complement-mediated diseases. In particular, complement …
Usefulness and analytical performances of complement multiplex assay for measuring complement biomarkers in plasma
MS Meuleman, A Duval, A Grunenwald, MR Artero… - Clinica Chimica …, 2024 - Elsevier
Introduction The complement system is involved in numerous diseases, through diverse
mechanisms and degree of activation. With the emergence of complement targeting …
mechanisms and degree of activation. With the emergence of complement targeting …
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