Background Cross-sectional genome-wide association studies have identified hundreds of
loci associated with blood lipids and related cardiovascular traits, but few genetic …

Importance New drugs which provide benefit alongside statin mono-therapy are warranted
to reduce risk of cardiovascular disease. Objective To systematically evaluate the genetically …

Background Circulating lipoprotein lipids cause coronary heart disease (CHD). However,
the precise way in which one or more lipoprotein lipid-related entities account for this …

The past few years have seen significant advances in the identification of genetic factors that
contribute to complex disease. Progress in cardiovascular diseases (CVD) has been …

Background Cardiovascular disease (CVD) and its most common manifestations–including
coronary heart disease (CHD), stroke, heart failure (HF), and atrial fibrillation (AF)–are major …

Cardiovascular disease risk prediction using genetic informa... : Current Opinion in
Lipidology Cardiovascular disease risk prediction using genetic information (gene scores) …

The goal of genetic studies for lipid levels is to improve treatment and ultimately reduce the
prevalence of heart disease. Many signals identified by GWAS have modest effect sizes …

Accurate disease risk stratification can lead to more precise and personalized prevention
and treatment of diseases. As an important component to disease risk, genetic risk factors …

Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied
prevalence worldwide owing to different dietary patterns and medication use. Despite …

Background The association between genetic variations of vascular endothelial growth
factor (VEGF) gene and the risk for atherosclerosis has been hypothesized. We aimed to …