The physiological role of the renin angiotensin aldosterone system (RAAS) is to maintain the
integrity of the cardiovascular system. The effect of angiotensin II is mediated via the …

Abstract Abstract Valsartan (Diovan®) is an oral angiotensin II-receptor antagonist with
specificity for the angiotensin II type 1 receptor subtype. It demonstrates antihypertensive …

Survivors of myocardial infarction (MI) are at high risk of disability and death. This is due to
infarct-related complications such as heart failure, cardiac remodeling with progressive …

Background Angiotensin-converting–enzyme (ACE) inhibitors such as captopril reduce
mortality and cardiovascular morbidity among patients with myocardial infarction …

Background Survivors of acute myocardial infarction (MI) complicated by heart failure and/or
resulting in left ventricular dysfunction are at heightened risk for subsequent death and …

Background Actions of angiotensin II may contribute to the progression of heart failure
despite treatment with currently recommended drugs. We therefore evaluated the long-term …

Angiotensin-converting enzyme inhibitors (ACE-Is) are an evidence-based treatment for
patients who after myocardial infarction (MI) present with either heart failure (HF) or left …

Blockade of the renin–angiotensin system by angiotensin converting enzyme (ACE)
inhibitors reduces mortality and morbidity in patients post-myocardial infarction as well as in …

Treatment of acute myocardial infarction (MI) has been advanced considerably in the past
20 years with the advent of acute reperfusion strategies such as thrombolytic therapy or …

Abstract Background: The VALsartan In Acute myocardial iNfarcTion (VALIANT) trial
compared outcomes with:(1) angiotensin‐converting enzyme inhibition (ACEI) with the …