1. Ubiquitin immunohistochemistry was used for investigation of time dependent changes of
ubiquitin in the nerve cells reacting to ischemic/reperfusion damage. In the rabbit spinal cord …

Short term sublethal ischemia or ischemic preconditioning gives protection to the neurons
against subsequent lethal ischemic attack. This so-called ischemic tolerance can also be …

Ubiquitin is involved in the degradation of denatured proteins in the recovery process after
various stresses. To clarify the different responses of the ubiquitin system in the …

Background and Purpose—Vulnerability of motor neurons in the spinal cord against
ischemia is considered to play an important role in the development of delayed paraplegia …

Using immunohistochemistry, we visualized the localization of ubiquitin in the gerbil
hippocampus following 3 min of ischemia with or without pretreatment with 2 min of …

Ubiquitin binds to short-lived proteins and denatured proteins produced by various forms of
injury. The loss of ubiquitin leads to an accumulation of abnormal proteins and may affect …

Ubiquitin, an essential protein in nonlysosomal proteolytic system, is expressed after
metabolic stress to the cell, The authors investigated stress response of ubiquitin in the …

The ubiquitin-mediated proteolytic pathway is an important mode of protein degradation in
various tissues. Since breakdown of proteins may occur in axons after injury we evaluated …

Accumulation of mutant ubiquitin-B (UBB+ 1) in neurons is considered the hallmark of
proteasomal dysfunction in neurodegenerative disorders, however no such evidence in …

Two hours of transient focal brain ischemia causes acute neuronal death in the striatal core
region and a somewhat more delayed type of neuronal death in neocortex. The objective of …