HPV status is associated with altered PIWI-interacting RNA expression pattern in head and neck cancer

N Firmino, VD Martinez, DA Rowbotham, KSS Enfield… - Oral oncology, 2016 - Elsevier
Objectives As HPV-induced cases of oral malignancy increase, it is important to understand
the molecular differences between HPV positive and negative head and neck squamous cell …

[HTML][HTML] Piwi-interacting RNAs and PIWI genes as novel prognostic markers for breast cancer

P Krishnan, S Ghosh, K Graham, JR Mackey… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract Piwi-interacting RNAs (piRNAs), whose role in germline maintenance has been
established, are now also being classified as post-transcriptional regulators of gene …

[HTML][HTML] Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal …

W Weng, N Liu, Y Toiyama, M Kusunoki, T Nagasaka… - Molecular cancer, 2018 - Springer
Background Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) may be
important epigenetic regulators of gene expression in human cancers; however, their …

Mitochondrial PIWI-interacting RNAs are novel biomarkers for clear cell renal cell carcinoma

C Zhao, Y Tolkach, D Schmidt, M Toma… - World Journal of …, 2019 - Springer
Abstract Purpose PIWI-interacting RNAs (piRNAs) have been suggested to serve as
biomarkers in cancer. In this study, we validated the expression profile of two piRNAs …

[HTML][HTML] Identification of piRNA targets in urinary extracellular vesicles for the diagnosis of prostate cancer

Q Peng, PKF Chiu, CYP Wong, CKL Cheng, JYC Teoh… - Diagnostics, 2021 - mdpi.com
Emerging studies demonstrate that PIWI-interacting RNAs (piRNAs) are associated with
various human cancers. This study aimed to evaluate the urinary extracellular vesicles (EVs) …

The burgeoning importance of PIWI-interacting RNAs in cancer progression

X Deng, T Liao, J Xie, D Kang, Y He, Y Sun… - Science China Life …, 2024 - Springer
PIWI-interacting RNAs (piRNAs) are a class of small noncoding RNA molecules that
specifically bind to piwi protein family members to exert regulatory functions in germ cells …

piRNA‐31115 Promotes Cell Proliferation and Invasion via PI3K/AKT Pathway in Clear Cell Renal Carcinoma

X Du, H Li, X Xie, L Shi, F Wu, G Li, C Lai… - Disease …, 2021 - Wiley Online Library
PIWI‐interacting RNAs (piRNAs) are small noncoding RNAs that play important roles in
germline development and carcinogenesis. In this study, we used the deep sequencing of …

Differential expressions analysis of piwi-interacting RNAs in hepatocellular carcinoma

PZ Miao, Y Yang, EB Chen, GQ Zhu… - Zhonghua gan Zang …, 2018 - europepmc.org
Objective: To investigates the role of piwi-interacting RNAs (piRNA) in the occurrence and
development of hepatocellular carcinoma. Methods: Second-generation small RNA …

[HTML][HTML] Piwi-interacting RNAs (piRNAs) are dysregulated in renal cell carcinoma and associated with tumor metastasis and cancer-specific survival

Y Li, X Wu, H Gao, JM Jin, AX Li, YS Kim, SK Pal… - Molecular …, 2015 - Springer
Piwi-interacting RNAs (piRNAs) are a distinct group of small noncoding RNAs (sncRNAs)
that silence transposable genetic elements to protect genome integrity. Because of their …

Circulating PIWI-interacting RNAs piR-5937 and piR-28876 are promising diagnostic biomarkers of colon cancer

P Vychytilova-Faltejskova, K Stitkovcova… - … Biomarkers & Prevention, 2018 - AACR
Background: The early detection of colon cancer is one of the main prerequisites for
successful treatment and mortality reduction. Circulating PIWI-interacting RNAs (piRNA) …