A serum piRNA signature as promising non-invasive diagnostic and prognostic biomarkers for colorectal cancer

A Qu, W Wang, Y Yang, X Zhang, Y Dong… - Cancer management …, 2019 - Taylor & Francis
Purpose: Piwi-interacting RNAs (piRNAs) are a novel class of small non-coding RNAs,
which are not easily degraded but detectable in human body fluids. Recent studies have …

Prediction of cancer-associated piRNA–mRNA and piRNA–lncRNA interactions by integrated analysis of expression and sequence data

Y Liu, J Zhang, A Li, Z Liu, Z He… - Tsinghua Science and …, 2018 - ieeexplore.ieee.org
piwi-interacting RNAs (piRNAs) are valuable biomarkers, but functional studies are still very
limited. Recent research shows that piRNA-mediated cleavage acts on Transposable …

[HTML][HTML] The disease-related biological functions of PIWI-interacting RNAs (piRNAs) and underlying molecular mechanisms

T Sun, X Han - ExRNA, 2019 - Springer
More than a decade ago, PIWI-interacting RNA (piRNA) was discovered almost
simultaneously by four different research groups. The length of this type of single stranded …

PIWI-interacting RNA 021285 is involved in breast tumorigenesis possibly by remodeling the cancer epigenome

A Fu, DI Jacobs, AE Hoffman, T Zheng, Y Zhu - Carcinogenesis, 2015 - academic.oup.com
Abstract Although PIWI-interacting RNAs (piRNAs) account for the largest class of the small
non-coding RNA superfamily, virtually nothing is known of their function in human …

Serum PIWI-interacting RNAs piR-020619 and piR-020450 are promising novel biomarkers for early detection of colorectal cancer

Z Wang, H Yang, D Ma, Y Mu, X Tan, Q Hao… - … Biomarkers & Prevention, 2020 - AACR
Background: Early diagnosis can significantly reduce colorectal cancer deaths. We sought to
identify serum PIWI-interacting RNAs (piRNAs) that could serve as sensitive and specific …

[HTML][HTML] PIWI-interacting RNAs: new biomarkers for diagnosis and treatment of breast cancer

P Maleki Dana, MA Mansournia, SM Mirhashemi - Cell & Bioscience, 2020 - Springer
Cancer is one of the most important reasons of mortality in the world. However, there are
several therapeutic platforms to treat patients who suffering from cancer common treatments …

[HTML][HTML] The emerging role of the piRNA/piwi complex in cancer

Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …

Expression levels of PIWI-interacting RNA, piR-823, are deregulated in tumor tissue, blood serum and urine of patients with renal cell carcinoma

R Iliev, M Fedorko, T Machackova… - Anticancer …, 2016 - ar.iiarjournals.org
Background: Renal cell carcinoma (RCC) is the most common neoplasm of adult kidney
accounting for about 3% of adult malignancies. P-Element induced wimpy testis (PIWI) …

[HTML][HTML] Genome-wide profiling of the PIWI-interacting RNA-mRNA regulatory networks in epithelial ovarian cancers

G Singh, J Roy, P Rout, B Mallick - PloS one, 2018 - journals.plos.org
PIWI-interacting (piRNAs),~ 23–36 nucleotide-long small non-coding RNAs (sncRNAs),
earlier believed to be germline-specific, have now been identified in somatic cells, including …

[HTML][HTML] PIWI-interacting RNAs (piRNAs): Promising applications as emerging biomarkers for digestive system cancer

A Cai, Y Hu, Z Zhou, Q Qi, Y Wu, P Dong… - Frontiers in Molecular …, 2022 - frontiersin.org
PIWI-interacting RNAs (piRNAs) are a novel type of small non-coding RNAs (sncRNAs),
which are 26–31 nucleotides in length and bind to PIWI proteins. Although piRNAs were …