Emerging functions of piwi‐interacting RNAs in diseases

K Wang, T Wang, XQ Gao, XZ Chen… - Journal of cellular …, 2021 - Wiley Online Library
PIWI‐interacting RNAs (piRNAs) are recently discovered small non‐coding RNAs consisting
of 24‐35 nucleotides, usually including a characteristic 5‐terminal uridine and an adenosine …

[HTML][HTML] Small RNA Profiling of piRNAs in Colorectal Cancer Identifies Consistent Overexpression of piR-24000 That Correlates Clinically with an Aggressive Disease …

DN Iyer, TMH Wan, JHW Man, RWY Sin, X Li, OSH Lo… - Cancers, 2020 - mdpi.com
Piwi-interacting RNAs (piRNAs) represent a novel class of small non-coding RNAs
(ncRNAs) that have been shown to have a deregulated expression in several cancers …

[HTML][HTML] Piwi-interacting RNAs in cancer: emerging functions and clinical utility

KW Ng, C Anderson, EA Marshall, BC Minatel… - Molecular cancer, 2016 - Springer
PIWI-interacting RNAs (piRNAs) are emerging players in cancer genomics. Originally
described in the germline, there are over 20,000 piRNA genes in the human genome. In …

[HTML][HTML] Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases

Z Wu, X Yu, S Zhang, Y He, W Guo - Cell Communication and Signaling, 2023 - Springer
Non-coding RNA has aroused great research interest recently, they play a wide range of
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …

Systematic evaluation of the effects of genetic variants on PIWI-interacting RNA expression across 33 cancer types

J Xin, M Du, X Jiang, Y Wu, S Ben… - Nucleic Acids …, 2021 - academic.oup.com
PIWI-interacting RNAs (piRNAs) are an emerging class of non-coding RNAs involved in
tumorigenesis. Expression quantitative trait locus (eQTL) analysis has been demonstrated to …

Investigating piwi‐interacting RNA regulome in human neuroblastoma

J Roy, B Mallick - Genes, Chromosomes and Cancer, 2018 - Wiley Online Library
Remarkable attempts have been exercised in recent years using high‐throughput
technologies to identify and decipher the functions of piRNAs in various abnormalities like …

piRSNP: A Database of piRNA-related SNPs and their Effects on Cancerrelated piRNA Functions

Y Liu, A Li, Y Zhu, X Pang, X Hei, G Xie… - Current …, 2023 - ingentaconnect.com
Background: PIWI-interacting RNAs (piRNAs) are a kind of small non-coding RNAs which
interact with PIWI proteins and play a vital role in safeguarding genome. Single nucleotide …

PIWI-interacting RNAs: critical roles and therapeutic targets in cancer

J Zhou, H Xie, J Liu, R Huang, Y Xiang, D Tian, E Bian - Cancer Letters, 2023 - Elsevier
P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a novel class of small
regulatory RNAs (approximately 24–31 nucleotides in length) that often bind to members of …

[HTML][HTML] The emerging role of PIWI-interacting RNAs (piRNAs) in gastrointestinal cancers: An updated perspective

I Riquelme, P Pérez-Moreno, P Letelier, P Brebi… - Cancers, 2021 - mdpi.com
Simple Summary Gastrointestinal (GI) cancers are high mortality malignancies due to late
diagnosis, the presence of metastasis and drug resistance development. Novel and more …

[PDF][PDF] PIWI proteins and PIWI-interacting RNA: emerging roles in cancer

YN Han, Y Li, SQ Xia, YY Zhang, JH Zheng… - Cellular Physiology and …, 2018 - karger.com
P-Element induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a type of noncoding
RNAs (ncRNAs) and interact with PIWI proteins. piRNAs were primarily described in the …