Novel perspectives for the diagnosis and treatment of gynecological cancers using Dysregulation of PIWI Protein and PiRNAs as biomarkers

B Yousefi, F Sadoughi, Z Asemi… - Current Medicinal …, 2024 - ingentaconnect.com
The term “gynecological cancer” is used for a group of cancers occurring in the female
reproductive system. Some of these cancers are ranked as the leading causes of death in …

[HTML][HTML] Potential roles of PIWI-interacting RNAs in lung cancer

Z Jian, Y Han, H Li - Frontiers in Oncology, 2022 - frontiersin.org
Lung cancer is a malignant tumor with high morbidity and mortality in the world today.
Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) are aberrantly expressed …

[HTML][HTML] piR-651 promotes tumor formation in non-small cell lung carcinoma through the upregulation of cyclin D1 and CDK4

D Li, Y Luo, Y Gao, Y Yang… - International …, 2016 - spandidos-publications.com
Piwi-interacting RNAs (piRNAs or piRs) are a novel class of non-coding RNAs that
participate in germline development by silencing transposable elements and regulating …

[HTML][HTML] piR-19166 inhibits migration and metastasis through CTTN/MMPs pathway in prostate carcinoma

T Qi, H Cao, H Sun, H Feng, N Li, C Wang… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Tumor metastasis is one of death causes for patients of prostate carcinoma. PIWI-interacting
RNAs (piRNAs) are a subtype of noncoding protein RNAs that are involved in …

piRNA: A promising biomarker in early detection of gastrointestinal cancer

MA Mojarad, MA Mojarad, B Shojaee… - … -Research and Practice, 2022 - Elsevier
Gastrointestinal (GI) cancer has become the primary concern of today's society due to its
aggressive nature and poor prognosis. PIWI-interacting RNAs (piRNAs), a subgroup of non …

[HTML][HTML] piRNA-8041 is downregulated in human glioblastoma and suppresses tumor growth in vitro and in vivo

DI Jacobs, Q Qin, A Fu, Z Chen, J Zhou, Y Zhu - Oncotarget, 2018 - ncbi.nlm.nih.gov
PIWI-interacting RNAs (piRNAs) are small non-coding RNAs that partner with PIWI proteins
to protect germline tissues from destabilizing transposon activity. While the aberrant …

PIWIL1 interacting RNA piR-017061 inhibits pancreatic cancer growth via regulating EFNA5

J Xie, S Xing, BY Shen, HT Chen, B Sun, ZT Wang… - Human Cell, 2021 - Springer
PIWI (P element induced wimpy testis) integrating RNAs (piRNAs) are small non-coding
RNAs with the length of approximately 30 nucleotides that plays crucial roles in germ cells …

Potential roles of PIWI-interacting RNAs in breast cancer, a new therapeutic strategy

H Zhang, Y Li - Pathology-Research and Practice, 2024 - Elsevier
Breast cancer (BC) has been the focus of numerous studies aimed at identifying novel
biological markers for its early detection. PIWI-interacting RNAs (piRNAs), a subset of small …

[HTML][HTML] PiRNA Obtained through Liquid Biopsy as a Possible Cancer Biomarker

P Limanówka, B Ochman, E Świętochowska - Diagnostics, 2023 - mdpi.com
In recent years PIWI-interacting RNAs (piRNAs) have gained the interest of scientists, mainly
because of their possible implications in cancer. Many kinds of research showed how their …

[HTML][HTML] Emerging roles of piRNAs in cancer: challenges and prospects

YE Cheng, Q Wang, W Jiang, Y Bian, A Gou… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
PiRNAs are a small class of non-coding small RNAs newly discovered in recent years.
Millions of piRNAs have been discovered to date, and more than 20,000 piRNA genes have …