Intercellular communication plays a critical role in the ever-evolving landscape of invasive
cancers. Recent studies have elucidated the potential role of tunneling nanotubes (TNTs) in …

Tunneling nanotubes (TNTs) are thin membrane tubes connecting remote cells and allowing
the transfer of cellular content. TNTs have been reported in several cancer in vitro, ex vivo …

Currently Cancer is the leading cause of death worldwide. Malignancy or cancer is a class of
diseases characterized by uncontrolled cell growth that eventually invade other tissues and …

Tunneling nanotubes are actin-based cytoplasmic extensions that function as intercellular
channels in a wide variety of cell types. There is a renewed and keen interest in the …

The interaction between tumor cells and macrophages is crucial in promoting tumor invasion
and metastasis. In this study, we examined a novel mechanism of intercellular …

Tunneling nanotubes (TNTs) are intercellular conduits, which meet the communication
needs of non-adjacent cells situated in the same tissue but at distances up to a few hundred …

In this study, we demonstrated that hypoxic conditions stimulated an increase in tunneling
nanotube (TNT) formation in chemoresistant ovarian cancer cells (SKOV3, C200). We found …

Tunneling nanotubes (TnTs) are thin channels that temporally connect nearby cells allowing
the cell-to-cell trafficking of biomolecules and organelles. The presence or absence of TnTs …

It is well established that the role of the tumor microenvironment (TME) in cancer
progression and therapeutic resistance is crucial, but many of the underlying mechanisms …

Intercellular communication is vital to the ecosystem of cancer cell organization and
invasion. Identification of key cellular cargo and their varied modes of transport are important …