Tissue hypoxia/ischemia is a pathological feature of many human disorders including stroke,
myocardial infarction, hypoxic/ischemic nephropathy, as well as cancer. In the kidney, the …

Mitogen activated protein kinases (MAPKs) are intracellular signal transduction molecules,
which connect cell‐surface receptor signals to intracellular processes. MAPKs regulate a …

The extracellular signal-regulated kinase (ERK) and Akt have been reported to be activated
by ischemia/reperfusion in vivo. However, the signaling pathways involved in activation of …

Mitogen-activated protein kinase (MAPK) cascades contain a trio of kinases, MAPK kinase
kinase (MKKK)→ MAPK kinase (MKK)→ MAPK, that mediate a variety of cellular responses …

This paper focuses on the role that mitogen‐activated protein kinases (MAPKs) play in drug‐
induced kidney injury. The MAPKs, of which there are four major classes (ERK, p38, JNK …

Mitogen-activated protein kinases (MAPK) play a key role in the regulation of cellular
processes such as cell growth, cell differentiation, and apoptosis. However, the specific …

Recent studies have revealed that mitogen-activated protein kinase (MAPK) consists of at
least three subfamilies, namely classical MAPK (also known as ERK), stress-activated …

Mitogen-activated protein kinases (MAP kinases) are functionally connected kinases that
regulate key cellular process involved in kidney disease such as all survival, death …

Following an overview of the biochemistry of mitogen-activated protein kinase (MAPK)
pathways, the relevance of these signaling events to specific models of renal cell function …

Mammalian cells respond to external stimuli by activation of a variety of signal transduction
pathways which culminate in stereotypical responses important in renal disease, such as …