Natural products discovery needs improved taxonomic and geographic information

MC Leal, A Hilário, MHG Munro, JW Blunt… - Natural product …, 2016 - pubs.rsc.org
Covering: up to 2016 Marine and terrestrial organisms yield a remarkable chemical diversity
and are important sources for discovery of new chemical products. In order to maximize the …

The landscape of natural product diversity and their pharmacological relevance from a focus on the Dictionary of Natural Products®

F Chassagne, G Cabanac, G Hubert, B David… - Phytochemistry …, 2019 - Springer
Nature is considered a prolific source of diverse biologically active chemotypes. While most
reviews have focused on the characteristics of the chemical backbones of natural products …

How different are marine microbial natural products compared to their terrestrial counterparts?

TM Voser, MD Campbell, AR Carroll - Natural Product Reports, 2022 - pubs.rsc.org
Covering: 1877 to 2020 A key challenge in natural products research is the selection of
biodiversity to yield novel chemistry. Recently, marine microorganisms have become a …

Trends in the discovery of new marine natural products from invertebrates over the last two decades–where and what are we bioprospecting?

MC Leal, J Puga, J Serodio, NCM Gomes, R Calado - PLoS One, 2012 - journals.plos.org
It is acknowledged that marine invertebrates produce bioactive natural products that may be
useful for developing new drugs. By exploring untapped geographical sources and/or novel …

Retrospective analysis of natural products provides insights for future discovery trends

CR Pye, MJ Bertin, RS Lokey… - Proceedings of the …, 2017 - National Acad Sciences
Understanding of the capacity of the natural world to produce secondary metabolites is
important to a broad range of fields, including drug discovery, ecology, biosynthesis, and …

Bioprospecting of marine invertebrates for new natural products—A chemical and zoogeographical perspective

MC Leal, C Madeira, CA Brandão, J Puga, R Calado - Molecules, 2012 - mdpi.com
Bioprospecting for new marine natural products (NPs) has increased significantly over the
last decades, leading to an unprecedented discovery of new molecules. Marine …

Natural products and drug discovery: A survey of stakeholders in industry and academia

V Amirkia, M Heinrich - Frontiers in pharmacology, 2015 - frontiersin.org
Context: In recent decades, natural products have undisputedly played a leading role in the
development of novel medicines. Yet, trends in the pharmaceutical industry at the level of …

Biogeography and biodiscovery hotspots of macroalgal marine natural products

MC Leal, MHG Munro, JW Blunt, J Puga… - Natural product …, 2013 - pubs.rsc.org
Coverage period: 1965 to 2012This review covers the literature published for marine natural
products isolated from macroalgae and addresses the taxonomic details of source …

Analysis and purification of bioactive natural products: the AnaPurNa study

GF Pauli, SN Chen, JB Friesen… - Journal of natural …, 2012 - ACS Publications
Based on a meta-analysis of data mined from almost 2000 publications on bioactive natural
products (NPs) from> 80 000 pages of 13 different journals published in 1998–1999, 2004 …

Guidelines for consistent characterisation and documentation of plant source materials for studies in phytochemistry and phytopharmacology

C Zidorn - Phytochemistry, 2017 - Elsevier
Plants are still by far the most important source of natural products. For higher plants as
source materials identification and documentation are less challenging than for many other …