The development of cancer vaccines has been intensively pursued over the past 50 years
with modest success. However, recent advancements in the fields of genetics, molecular …

There are strong biologic and preclinical rationales for the development of therapeutic
cancer vaccines; however, the clinical translation of this treatment strategy has been …

Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The
conventional treatment options for cancer have numerous challenges, such as a low blood …

Vaccines are an important tool in the rapidly evolving repertoire of immunotherapies in
oncology. Although cancer vaccines have been investigated for over 30 years, very few …

The first generation of human cancer vaccines has been tested in phase III clinical trials, but
only a few of these have demonstrated sufficient efficacy to be licensed for clinical use. This …

Advancements in knowledge in diverse fields of science, including genetics, cell biology,
molecular biology and biochemistry, have shed light on the origins of cancer and cell …

Cancer vaccines have been shown clinically to drive tumor-reactive cell activation,
proliferation, and effector function. Unfortunately, tumor eradication by treatment with cancer …

Background: Cancer vaccines are a unique approach to cancer therapy. They exert an
antitumor effect by engaging the host immune response, and have great potential for …

The advent of cancer immunotherapy has revolutionized the field of cancer treatment and
offers cancer patients new hope. Although this therapy has proved highly successful for …

Therapeutic vaccines are currently at the forefront of medical innovation. Various endeavors
have been made to develop more consolidated approaches to producing nucleic acid …