Oestradiol enhances testosterone-induced suppression of human spermatogenesis
DJ Handelsman, S Wishart, AJ Conway - Human Reproduction, 2000 - academic.oup.com
The aim of this study was to determine for the first time in humans, the efficacy of adding a
low dose oestradiol to a suboptimally suppressive testosterone dose in a depot hormonal …
low dose oestradiol to a suboptimally suppressive testosterone dose in a depot hormonal …
Suppression of human spermatogenesis by depot androgen: potential for male contraception
RS Swerdloff, LA Campfield, A Palacios… - Journal of Steroid …, 1979 - Elsevier
The gonadotropic hormones, LH and FSH, are required for normal sperm production.
Inhibition of gonadotropin secretion by exogenously administered sex steroids represents …
Inhibition of gonadotropin secretion by exogenously administered sex steroids represents …
Combined administration of levonorgestrel and testosterone induces more rapid and effective suppression of spermatogenesis than testosterone alone: a promising …
RA Bebb, BD Anawalt, RB Christensen… - The Journal of …, 1996 - academic.oup.com
Studies using high dose testosterone (T) administration in normal men as a male
contraceptive have resulted in azoospermia rates of only 50-70%. Previous studies of T and …
contraceptive have resulted in azoospermia rates of only 50-70%. Previous studies of T and …
Depot testosterone with etonogestrel implants result in induction of azoospermia in all men for long-term contraception
BM Brady, M Walton, N Hollow, AT Kicman… - Human …, 2004 - academic.oup.com
BACKGROUND: Combined testosterone and progestogen preparations are a promising
approach to male hormonal contraception. We investigated the effect of sc etonogestrel with …
approach to male hormonal contraception. We investigated the effect of sc etonogestrel with …
Recent advances in hormonal male contraception
MC Meriggiola, A Costantino, S Cerpolini - Contraception, 2002 - Elsevier
Hormones inhibit fertility in men by suppressing sperm production. Testosterone-enanthate
induced azoospermia has proven to provide optimal contraceptive protection. Preliminary …
induced azoospermia has proven to provide optimal contraceptive protection. Preliminary …
Is high dosage testosterone an effective male contraceptive agent?
AM Matsumoto - Fertility and sterility, 1988 - Elsevier
In male contraceptive trials, approximately half of normal men become azoospermic on high
dosages of testosterone enanthate (TE), whereas the other half of men become severely …
dosages of testosterone enanthate (TE), whereas the other half of men become severely …
Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. I: Plasma luteinizing hormone, follicle …
EM Wallace, SM Gow, FC Wu - The Journal of Clinical …, 1993 - academic.oup.com
Sex-steroid based male contraceptive regimes induce azoospermia in only 40-70% of
Caucasian men. The reason (s) why the remainder maintains a low level of …
Caucasian men. The reason (s) why the remainder maintains a low level of …
Suppression of spermatogenesis by etonogestrel implants with depot testosterone: potential for long-acting male contraception
RA Anderson, D Kinniburgh… - The Journal of Clinical …, 2002 - academic.oup.com
The coadministration of a progestogen with testosterone increases the degree of
suppression of spermatogenesis and is one approach to the development of hormonal male …
suppression of spermatogenesis and is one approach to the development of hormonal male …
Determinants of the rate and extent of spermatogenic suppression during hormonal male contraception: an integrated analysis
PY Liu, RS Swerdloff, BD Anawalt… - The Journal of …, 2008 - academic.oup.com
Context: Male hormonal contraceptive methods require effective suppression of sperm
output. Objective: The objective of the study was to define the covariables that influence the …
output. Objective: The objective of the study was to define the covariables that influence the …
Suppression of spermatogenesis by exogenous testosterone
F Fusco, P Verze, M Capece… - Current Pharmaceutical …, 2021 - ingentaconnect.com
Sperm production starts from puberty in the seminiferous tubules providing testosterone
production by the Leydig cells that takes place in the interstice of the testicles. Normal …
production by the Leydig cells that takes place in the interstice of the testicles. Normal …