Distinct roles of dorsal and ventral subthalamic neurons in action selection and cancellation

CP Mosher, AN Mamelak, M Malekmohammadi… - Neuron, 2021 - cell.com
The subthalamic nucleus (STN) supports action selection by inhibiting all motor programs
except the desired one. Recent evidence suggests that STN can also cancel an already …

A selective role for ventromedial subthalamic nucleus in inhibitory control

B Pasquereau, RS Turner - Elife, 2017 - elifesciences.org
The subthalamic nucleus (STN) is hypothesized to play a central role in the rapid stopping of
movement in reaction to a stop signal. Single-unit recording evidence for such a role is …

Neuronal activity in the human subthalamic nucleus encodes decision conflict during action selection

KA Zaghloul, CT Weidemann, BC Lega… - Journal of …, 2012 - Soc Neuroscience
The subthalamic nucleus (STN), which receives excitatory inputs from the cortex and has
direct connections with the inhibitory pathways of the basal ganglia, is well positioned to …

Inhibitory control and error monitoring by human subthalamic neurons

J Bastin, M Polosan, D Benis, L Goetz… - Translational …, 2014 - nature.com
The subthalamic nucleus (STN) has been shown to be implicated in the control of voluntary
action, especially during tasks involving conflicting choice alternatives or rapid response …

Human subthalamic nucleus activity during non-motor decision making

BA Zavala, AI Jang, KA Zaghloul - Elife, 2017 - elifesciences.org
Recent studies have implicated the subthalamic nucleus (STN) in decisions that involve
inhibiting movements. Many of the decisions that we make in our daily lives, however, do not …

The subthalamic nucleus: unravelling new roles and mechanisms in the control of action

T Bonnevie, KA Zaghloul - The Neuroscientist, 2019 - journals.sagepub.com
How do we decide what we do? This is the essence of action control, the process of
selecting the most appropriate response among multiple possible choices. Suboptimal …

Subthalamic nucleus activity dissociates proactive and reactive inhibition in patients with Parkinson's disease

D Benis, O David, JP Lachaux, E Seigneuret, P Krack… - Neuroimage, 2014 - Elsevier
Abstract Models of action selection postulate the critical involvement of the subthalamic
nucleus (STN), especially in reactive inhibition processes when inappropriate responses to …

Role for subthalamic nucleus neurons in switching from automatic to controlled eye movement

M Isoda, O Hikosaka - Journal of Neuroscience, 2008 - Soc Neuroscience
The subthalamic nucleus (STN) of the basal ganglia is an important element of motor
control. This is demonstrated by involuntary movements induced by STN lesions and the …

The role of the subthalamic nucleus in cognition

DB Weintraub, KA Zaghloul - Reviews in the Neurosciences, 2013 - degruyter.com
Because the complex functions of the basal ganglia have been increasingly studied over the
past several decades, the understanding of the role of the subthalamic nucleus (STN) in …

Frontosubthalamic circuits for control of action and cognition

AR Aron, DM Herz, P Brown, BU Forstmann… - Journal of …, 2016 - Soc Neuroscience
The subthalamic nucleus (STN) of the basal ganglia appears to have a potent role in action
and cognition. Anatomical and imaging studies show that different frontal cortical areas …