Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria‐dependent pathway in human osteosarcoma U‐2 OS cells
Kaempferol is a natural flavonoid. Previous studies have reported that kaempferol has anti‐
proliferation activities and induces apoptosis in many cancer cell lines. However, there are …
proliferation activities and induces apoptosis in many cancer cell lines. However, there are …
[HTML][HTML] Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells
HS Lee, HJ Cho, R Yu, KW Lee, HS Chun… - International journal of …, 2014 - mdpi.com
We previously noted that kaempferol, a flavonol present in vegetables and fruits, reduced
cell cycle progression of HT-29 cells. To examine whether kaempferol induces apoptosis of …
cell cycle progression of HT-29 cells. To examine whether kaempferol induces apoptosis of …
[HTML][HTML] Kaempferol induced the apoptosis via cell cycle arrest in human breast cancer MDA-MB-453 cells
EJ Choi, WS Ahn - Nutrition research and practice, 2008 - synapse.koreamed.org
The aim of present study was to investigate the effects of kaempferol on cellular proliferation
and cell cycle arrest and explore the mechanism for these effects in human breast …
and cell cycle arrest and explore the mechanism for these effects in human breast …
[HTML][HTML] Kaempferol induces apoptosis in HepG2 cells via activation of the endoplasmic reticulum stress pathway
H Guo, F Ren, LI Zhang, X Zhang… - Molecular …, 2016 - spandidos-publications.com
Kaempferol is a flavonoid compound that has gained importance due to its antitumor
properties; however, the underlying mechanisms remain to be fully understood. The present …
properties; however, the underlying mechanisms remain to be fully understood. The present …
[HTML][HTML] Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells
HJ Chen, CM Lin, CY Lee, NC Shih… - Oncology …, 2013 - spandidos-publications.com
Kaempferol is a natural flavonoid that possesses anti-proliferative and apoptosis-inducing
activities in several cancer cell lines. In the present study, we investigated the anti-metastatic …
activities in several cancer cell lines. In the present study, we investigated the anti-metastatic …
Kaempferol suppresses cisplatin-induced apoptosis via inductions of heme oxygenase-1 and glutamate-cysteine ligase catalytic subunit in HEI-OC1 cells
SS Gao, BM Choi, XY Chen, RZ Zhu, Y Kim… - Pharmaceutical …, 2010 - Springer
Purpose The present study was undertaken to elucidate the chemoprotective mechanism of
kaempferol, which possesses anti-oxidative and anti-apoptotic properties. Methods House …
kaempferol, which possesses anti-oxidative and anti-apoptotic properties. Methods House …
[HTML][HTML] Kaempferol suppresses proliferation and induces cell cycle arrest, apoptosis, and DNA damage in breast cancer cells
L Zhu, L Xue - Oncology research, 2019 - ncbi.nlm.nih.gov
Kaempferol is a flavonoid that has been extensively investigated owing to its antitumor
effects. Nevertheless, little is known about its underlying mechanisms of action. We aimed to …
effects. Nevertheless, little is known about its underlying mechanisms of action. We aimed to …
Kaempferol induces apoptosis in two different cell lines via Akt inactivation, Bax and SIRT3 activation, and mitochondrial dysfunction
G Marfe, M Tafani, M Indelicato… - Journal of cellular …, 2009 - Wiley Online Library
Abstract Kaempferol (3, 4′, 5, 7‐tetrahydroxyflavone) is a flavonoid with anti‐and pro‐
oxidant activity present in various natural sources. Kaempferol has been shown to posses …
oxidant activity present in various natural sources. Kaempferol has been shown to posses …
Anti-cancer effect and underlying mechanism (s) of kaempferol, a phytoestrogen, on the regulation of apoptosis in diverse cancer cell models
SH Kim, KC Choi - Toxicological research, 2013 - Springer
Phytoestrogens exist in edible compounds commonly found in fruits or plants. For long
times, phytoestrogens have been used for therapeutic treatments against human diseases …
times, phytoestrogens have been used for therapeutic treatments against human diseases …
[HTML][HTML] Kaempferol induces G2/M cell cycle arrest via checkpoint kinase 2 and promotes apoptosis via death receptors in human ovarian carcinoma A2780/CP70 …
Y Gao, J Yin, GO Rankin, YC Chen - Molecules, 2018 - mdpi.com
Kaempferol is a widely distributed dietary flavonoid. Epidemiological studies have
demonstrated kaempferol consumption lowers the risk of ovarian cancer. Our previous …
demonstrated kaempferol consumption lowers the risk of ovarian cancer. Our previous …